Anesthetic management of a neonate with congenital diaphragmatic hernia under high-frequency oscillatory ventilation.

Autor: Edipoglu IS; Department of Anesthesiology, Health Sciences University, Suleymaniye Women Maternity and Child Diseases Training and Research Hospital., Celik F; Department of Anesthesiology, Health Sciences University, Suleymaniye Women Maternity and Child Diseases Training and Research Hospital., Ozdogan T; Department of NICU, Health Sciences University, Suleymaniye Women Maternity and Child Diseases Training and Research Hospital., Comert S; Department of NICU, Health Sciences University, Suleymaniye Women Maternity and Child Diseases Training and Research Hospital., Guvenc BH; Department of Pediatric Surgery, Health Sciences University, Bakirkoy Dr. Sadi Konuk Training and Research Hospital, Istanbul, Turkey.
Jazyk: angličtina
Zdroj: Clinics and practice [Clin Pract] 2018 Jun 25; Vol. 8 (2), pp. 1057. Date of Electronic Publication: 2018 Jun 25 (Print Publication: 2018).
DOI: 10.4081/cp.2018.1057
Abstrakt: Perioperative management of a neonate with congenital diaphragmatic hernia (CDH) is challenging because of pulmonary hypoplasia, pulmonary hypertension, and respiratory insufficiency. In this report, we present our intra-operative experience in a 4-days old and 3070 grams CDH neonate. He was admitted to neonatal intensive care unit and intubated due to severe respiratory insufficiency. He showed signs of severe pulmonary hypoplasia and his echocardiography revealed a cardiac dextroversion. The patient was relatively stabilized after four days under combined high-frequency oscillatory ventilation (HFOV) and inhaled nitric oxide (iNO). A corrective surgical intervention was sustained with dopamine, dobutamine, fentanyl and midazolam infusions. Ventilator settings were: 9 cmH 2 O MAP; 15-Hz frequency; 30 cmH 2 O amplitude and 55% FiO 2 . Venous-blood gas analysis indicated pH:7.38 pO 2 :36.2, pCO 2 :39.2 with SpO 2 :98%. We believe that HFOV and iNO combination is an effective alternative for the anesthetic management of CDH cases as it provides better gas exchange and less volutrauma.
Competing Interests: Conflict of interest: the authors declare no conflict of interest.
Databáze: MEDLINE