Juvenile dermatomyositis forty years on: Case report.

Autor: Rego de Figueiredo I; Unidade de Doenças Auto-imunes/Medicina 7.2, Hospital de Curry Cabral, Centro Hospitalar de Lisboa Central (CHLC), Portugal. Electronic address: inesregofigueiredo@gmail.com., Guerreiro Castro S; Unidade de Doenças Auto-imunes/Medicina 7.2, Hospital de Curry Cabral, Centro Hospitalar de Lisboa Central (CHLC), Portugal., Bernardino V; Unidade de Doenças Auto-imunes/Medicina 7.2, Hospital de Curry Cabral, Centro Hospitalar de Lisboa Central (CHLC), Portugal., Silva Nunes J; Serviço de Endocrinologia, Hospital de Curry Cabral, CHLC, Portugal., Alves P; Serviço de Radiologia, Hospital de Dona Estefânia, CHLC, Portugal., Moraes-Fontes MF; Unidade de Doenças Auto-imunes/Medicina 7.2, Hospital de Curry Cabral, Centro Hospitalar de Lisboa Central (CHLC), Portugal.
Jazyk: angličtina
Zdroj: Neuromuscular disorders : NMD [Neuromuscul Disord] 2018 Sep; Vol. 28 (9), pp. 791-797. Date of Electronic Publication: 2018 Jun 30.
DOI: 10.1016/j.nmd.2018.06.011
Abstrakt: We present a case report of a 42 year old female, diagnosed at the age of 3 with Juvenile Dermatomyositis. The clinical course was severe and refractory to immunosuppressive therapy. Currently, she is mostly affected by severe muscle atrophy, large joint contractures, calcinosis, and a lipodystrophy associated metabolic syndrome with hypertriglyceridemia, insulin resistance, high total testosterone and hepatic steatosis. She developed Hodgkin´s lymphoma in the course of her disease. Personalized therapeutic choices are discussed as regards juvenile dermatomyositis complications.
(Copyright © 2018 Elsevier B.V. All rights reserved.)
Databáze: MEDLINE
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