Content-specific activity in frontoparietal and default-mode networks during prior-guided visual perception.

Autor:	González-García C; National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, United States.; Department of Experimental Psychology, Ghent University, Ghent, Belgium., Flounders MW; National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, United States.; Neuroscience Institute, New York University Langone Medical Center, New York, United States., Chang R; National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, United States., Baria AT; National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, United States., He BJ; National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, United States.; Neuroscience Institute, New York University Langone Medical Center, New York, United States.; Departments of Neurology, New York University Langone Medical Center, New York, United States.; Departments of Neuroscience and Physiology, New York University Langone Medical Center, New York, United States.; Departments of Radiology, New York University Langone Medical Center, New York, United States.
Jazyk:	angličtina
Zdroj:	ELife [Elife] 2018 Jul 31; Vol. 7. Date of Electronic Publication: 2018 Jul 31.
DOI:	10.7554/eLife.36068
Abstrakt:	How prior knowledge shapes perceptual processing across the human brain, particularly in the frontoparietal (FPN) and default-mode (DMN) networks, remains unknown. Using ultra-high-field (7T) functional magnetic resonance imaging (fMRI), we elucidated the effects that the acquisition of prior knowledge has on perceptual processing across the brain. We observed that prior knowledge significantly impacted neural representations in the FPN and DMN, rendering responses to individual visual images more distinct from each other, and more similar to the image-specific prior. In addition, neural representations were structured in a hierarchy that remained stable across perceptual conditions, with early visual areas and DMN anchored at the two extremes. Two large-scale cortical gradients occur along this hierarchy: first, dimensionality of the neural representational space increased along the hierarchy; second, prior's impact on neural representations was greater in higher-order areas. These results reveal extensive and graded influences of prior knowledge on perceptual processing across the brain. Competing Interests: CG, MF, RC, AB, BH No competing interests declared
Databáze:	MEDLINE
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