| Autor: |
Elkheir SM; 1 Department of Obstetrics and Gynaecology, El Obeid Maternity Hospital, El Obeid, Sudan., Babiker ZO; 2 Sudan HIV/AIDS Working Group (SHAWG), Glasgow, UK.; 3 Department of Internal Medicine, College of Medicine and Health Sciences, United Arab Emirates University, Al Ain, UAE., Elamin SK; 1 Department of Obstetrics and Gynaecology, El Obeid Maternity Hospital, El Obeid, Sudan., Yassin MI; 1 Department of Obstetrics and Gynaecology, El Obeid Maternity Hospital, El Obeid, Sudan.; 4 Department of Obstetrics and Gynaecology, Faculty of Medicine & Health Sciences, University of Kordofan, El Obeid, Sudan., Awadalla KE; 1 Department of Obstetrics and Gynaecology, El Obeid Maternity Hospital, El Obeid, Sudan.; 4 Department of Obstetrics and Gynaecology, Faculty of Medicine & Health Sciences, University of Kordofan, El Obeid, Sudan., Bealy MA; 5 Diagnostic Centre, Faculty of Medicine & Health Sciences, University of Kordofan, El Obeid, Sudan., Agab Eldour AA; 6 Department of Pathology, Faculty of Medicine & Health Sciences, University of Kordofan, El Obeid, Sudan., Alloba FE; 2 Sudan HIV/AIDS Working Group (SHAWG), Glasgow, UK.; 7 The Liverpool Centre for Sexual Health, Royal Liverpool University Hospital, Liverpool, UK., Atabani SF; 2 Sudan HIV/AIDS Working Group (SHAWG), Glasgow, UK.; 8 Public Health Laboratory Birmingham, National Infection Service, Heart of England Foundation NHS Trust, Birmingham, UK., Osman HK; 2 Sudan HIV/AIDS Working Group (SHAWG), Glasgow, UK.; 8 Public Health Laboratory Birmingham, National Infection Service, Heart of England Foundation NHS Trust, Birmingham, UK., Babiker AG; 2 Sudan HIV/AIDS Working Group (SHAWG), Glasgow, UK.; 9 MRC Clinical Trials Unit at University College London, London, UK., Herieka EA; 2 Sudan HIV/AIDS Working Group (SHAWG), Glasgow, UK.; 10 Department of Genitourinary Medicine, Royal Bournemouth Hospital, Bournemouth, UK. |
| Abstrakt: |
Routine infectious diseases screening of Sudanese pregnant women has been patchy due to scarcity of healthcare resources and social stigma. We sought to determine the seroprevalence of HIV, hepatitis B, and syphilis among pregnant women attending antenatal care (ANC) at El Obeid Maternity Hospital in western Sudan. We also explored the association between these infections and a set of socio-demographic and maternal variables. Unlinked anonymous testing for HIV-1/2 antibodies, hepatitis B surface antigen, and Treponema pallidum antibodies was performed on residual blood samples collected during routine ANC (August 2016-March 2017). Seroprevalence of HIV was 1.13% (5/444; 95% CI 0.37-2.61%), hepatitis B 2.93% (13/444; 95% CI 1.57-4.95%), and syphilis 7.43% (33/444; 95% CI 5.17-10.28%). On bivariate analysis, there were no statistically significant associations between hepatitis B, syphilis, or a composite outcome including any of the three infections and age, stage of pregnancy, gravidity, parity, previous mode of delivery, history of blood transfusion, or husband polygamy. Urgent action is needed to scale up routine maternal screening for HIV, hepatitis B, and syphilis on an opt-out basis. Further research into the socio-demographic and behavioural determinants of these infections as well as their clinical outcomes is needed. |
