OpenSim: Simulating musculoskeletal dynamics and neuromuscular control to study human and animal movement.

Autor: Seth A; Department of Bioengineering, Stanford University, Stanford, California, United States of America., Hicks JL; Department of Bioengineering, Stanford University, Stanford, California, United States of America., Uchida TK; Department of Bioengineering, Stanford University, Stanford, California, United States of America., Habib A; Department of Bioengineering, Stanford University, Stanford, California, United States of America., Dembia CL; Department of Mechanical Engineering, Stanford University, Stanford, California, United States of America., Dunne JJ; Department of Bioengineering, Stanford University, Stanford, California, United States of America., Ong CF; Department of Bioengineering, Stanford University, Stanford, California, United States of America., DeMers MS; Department of Mechanical Engineering, Stanford University, Stanford, California, United States of America., Rajagopal A; Department of Mechanical Engineering, Stanford University, Stanford, California, United States of America., Millard M; Department of Bioengineering, Stanford University, Stanford, California, United States of America., Hamner SR; Department of Mechanical Engineering, Stanford University, Stanford, California, United States of America., Arnold EM; Department of Mechanical Engineering, Stanford University, Stanford, California, United States of America., Yong JR; Department of Mechanical Engineering, Stanford University, Stanford, California, United States of America., Lakshmikanth SK; Department of Bioengineering, Stanford University, Stanford, California, United States of America., Sherman MA; Department of Bioengineering, Stanford University, Stanford, California, United States of America., Ku JP; Department of Bioengineering, Stanford University, Stanford, California, United States of America., Delp SL; Department of Bioengineering, Stanford University, Stanford, California, United States of America.; Department of Mechanical Engineering, Stanford University, Stanford, California, United States of America.; Department of Orthopaedic Surgery, Stanford University, Stanford, California, United States of America.
Jazyk: angličtina
Zdroj: PLoS computational biology [PLoS Comput Biol] 2018 Jul 26; Vol. 14 (7), pp. e1006223. Date of Electronic Publication: 2018 Jul 26 (Print Publication: 2018).
DOI: 10.1371/journal.pcbi.1006223
Abstrakt: Movement is fundamental to human and animal life, emerging through interaction of complex neural, muscular, and skeletal systems. Study of movement draws from and contributes to diverse fields, including biology, neuroscience, mechanics, and robotics. OpenSim unites methods from these fields to create fast and accurate simulations of movement, enabling two fundamental tasks. First, the software can calculate variables that are difficult to measure experimentally, such as the forces generated by muscles and the stretch and recoil of tendons during movement. Second, OpenSim can predict novel movements from models of motor control, such as kinematic adaptations of human gait during loaded or inclined walking. Changes in musculoskeletal dynamics following surgery or due to human-device interaction can also be simulated; these simulations have played a vital role in several applications, including the design of implantable mechanical devices to improve human grasping in individuals with paralysis. OpenSim is an extensible and user-friendly software package built on decades of knowledge about computational modeling and simulation of biomechanical systems. OpenSim's design enables computational scientists to create new state-of-the-art software tools and empowers others to use these tools in research and clinical applications. OpenSim supports a large and growing community of biomechanics and rehabilitation researchers, facilitating exchange of models and simulations for reproducing and extending discoveries. Examples, tutorials, documentation, and an active user forum support this community. The OpenSim software is covered by the Apache License 2.0, which permits its use for any purpose including both nonprofit and commercial applications. The source code is freely and anonymously accessible on GitHub, where the community is welcomed to make contributions. Platform-specific installers of OpenSim include a GUI and are available on simtk.org.
Competing Interests: The authors have declared that no competing interests exist.
Databáze: MEDLINE
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