[The incidence and antibiotic resistance of common nosocomial uropathogens in the urine of urological patients in the Ivanovo region].

Autor:	Pochernikov DG; Department of Surgery and Urology, Ivanovo State Medical Academy of Minzdrav of Russia, Ivanovo, Russia., Strelnikov AI; Department of Surgery and Urology, Ivanovo State Medical Academy of Minzdrav of Russia, Ivanovo, Russia., Bazunov DS; Department of Surgery and Urology, Ivanovo State Medical Academy of Minzdrav of Russia, Ivanovo, Russia., Efimychev KA; Department of Surgery and Urology, Ivanovo State Medical Academy of Minzdrav of Russia, Ivanovo, Russia., Serdyutskaya US; Department of Surgery and Urology, Ivanovo State Medical Academy of Minzdrav of Russia, Ivanovo, Russia.
Jazyk:	ruština
Zdroj:	Urologiia (Moscow, Russia : 1999) [Urologiia] 2018 Jul (3), pp. 49-53.
Abstrakt:	Aim: To clarify the etiology of nosocomial UTIs occurring in the urology departments and the outpatient clinic of the Ivanovo Regional Clinical Hospital (IvRCH), to develop recommendations on the empirical use of antibiotic therapy. Materials and Methods: Bacterial composition of urine in urological patients was monitored from 1999 to 2015. The sensitivity of the pathogens to the main antibacterial agents was determined using the Kirby-Bauer disk diffusion susceptibility test. Results: The study determined the frequency of detecting pathogens associated with urinary tract infections in adults and children, established the association between the spectrum of pathogens and patient age and determined the most effective antibacterial drugs in patients with nosocomial UTI in the Ivanovo region. High resistance levels of E. coli strains were detected against fluoroquinolones, nalidixic acid, and nitrofurans; they were three times higher than that against cephalosporins. Conclusion: The findings show the need to reduce the empirical use of fluoroquinolones, nalidixic acid, and nitrofurans and completely exclude the use of ampicillin in patients with nosocomial UTI in the Ivanovo region. To reduce the occurrence of nosocomial infections, patients discharged from the hospital should be administered empirical therapy with third-generation cephalosporins.
Databáze:	MEDLINE
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