Relationship between blepharitis and components of the metabolic syndrome.

Autor: Pérez-Cano HJ; Centro de Investigación Biomédica, Fundación Hospital Nuestra Señora de la Luz I.A.P., Cuauhtémoc, Ciudad de México, México., Rubalcava-Soberanis ML; Consulta de Especialidad, Fundación Hospital Nuestra Señora de la Luz I.A.P., Cuauhtémoc, Ciudad de México, México., Velázquez Salgado R; Departamento de Bioquímica Aplicada, Facultad de Química, UNAM, Coyoacán, Ciudad de México, México. Electronic address: rvs_1604@hotmail.com.
Jazyk: English; Spanish; Castilian
Zdroj: Archivos de la Sociedad Espanola de Oftalmologia [Arch Soc Esp Oftalmol (Engl Ed)] 2018 Oct; Vol. 93 (10), pp. 476-480. Date of Electronic Publication: 2018 Jul 19.
DOI: 10.1016/j.oftal.2018.06.001
Abstrakt: Objective: To determine the relationship between the components of the metabolic syndrome with the presence of blepharitis.
Methods: The study included 60 patients with a diagnosis of blepharitis and 30 control subjects. Anthropometric measurements and blood pressure were recorded, and peripheral venous blood samples were obtained under fasting conditions to determine the concentration of Glucose, Cholesterol, and Triglycerides. High-density lipoprotein cholesterol (HDL-C) was determined after precipitating lipoproteins containing apoB-100 with phosphotungstic acid/Mg 2+ . The concentration of low density lipoprotein cholesterol (LDL-C) was calculated using the Friedewald formula modified by DeLong.
Results: In the comparative analysis, statistically significant differences were found in the waist circumference (P=.0491), systolic blood pressure (P=.0149), glucose (P=.0045), total cholesterol (P=.0001), HDL-C (P=.0049), LDL-C (P=.0266), and triglycerides (P=.0059); while there was no significant differences in the BMI or the diastolic pressure.
Conclusions: The results support the hypothesis that the metabolic syndrome could be considered a risk factor for the development of blepharitis, and its timely detection is essential to avoid future complications.
(Copyright © 2018 Sociedad Española de Oftalmología. Publicado por Elsevier España, S.L.U. All rights reserved.)
Databáze: MEDLINE
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