Acute responses of hemodynamic and oxidative stress parameters to aerobic exercise with blood flow restriction in hypertensive elderly women.

Autor: Barili A; Health Science Postgraduate Program, Unochapecó University, Servidão Anjo da Guarda Street, 295-D, Chapecó, SC, 89809-000, Brazil., Corralo VDS; Health Science Postgraduate Program, Unochapecó University, Servidão Anjo da Guarda Street, 295-D, Chapecó, SC, 89809-000, Brazil., Cardoso AM; Federal University of Fronteira Sul, Campus Chapecó, Chapecó, SC, Brazil., Mânica A; Molecular Biology and Biochemistry Department, Federal University of Santa Maria, Santa Maria, RS, Brazil., Bonadiman BDSR; Pharmacology Department, Federal University of Santa Maria, Santa Maria, RS, Brazil., Bagatini MD; Federal University of Fronteira Sul, Campus Chapecó, Chapecó, SC, Brazil., Da Silva-Grigoletto ME; Department of Physical Education, Federal University of Sergipe, Aracaju, SE, Brazil., de Oliveira GG; Federal University of Fronteira Sul, Campus Chapecó, Chapecó, SC, Brazil., De Sá CA; Health Science Postgraduate Program, Unochapecó University, Servidão Anjo da Guarda Street, 295-D, Chapecó, SC, 89809-000, Brazil. clodoaldo@unochapeco.edu.br.
Jazyk: angličtina
Zdroj: Molecular biology reports [Mol Biol Rep] 2018 Oct; Vol. 45 (5), pp. 1099-1109. Date of Electronic Publication: 2018 Jul 20.
DOI: 10.1007/s11033-018-4261-1
Abstrakt: Systemic arterial hypertension has been associated with the majority deaths from cardiovascular disease, especially among the elderly population, and the imbalance between antioxidant and pro-oxidants has been associated with hypertension. This study analyzed the acute responses of cardiorespiratory and oxidative stress parameters to low intensity aerobic exercise (LIAE) with blood flow restriction (BFR) in hypertensive elderly women. The experimental group consisted of 16 hypertensive women (67.2 ± 3.7 years) who underwent a progressive treadmill test and performed three exercise protocols in random order: high intensity (HIAE), low intensity aerobic exercise (LIAE) and low intensity aerobic exercise with blood flow restriction (LIAE + BFR). Data analysis showed that blood pressure and heart rate augmented from rest to post effort (p < 0.05) and reduced from post effort to recovery (p < 0.05) in all protocols. The values of lipid peroxidation were higher after 30 min of recovery when compared to the moment at rest in the LILIAE + BFR (p < 0.05). The same occurred with glutathione-S-transferase and superoxide dismutase activity. However, non-protein thiols levels (NPSH) reduced after 30 min of recovery when compared to the moment at rest in the LILIAE + BFR protocol (p < 0.05). In the HIAE and LIAE + BFR protocols, the levels of NPSH were lower at 30 min of recovery when compared to the same moment in the LIAE protocol (p < 0.05). LIAE + RBF produces an oxidative status and hemodynamic stimulus similar to HIAE. Taken together, these results support the indication of LIAE with BFR in chronic intervention protocols, with potential benefits for the hypertensive elderly population.
Databáze: MEDLINE