Computer-based cognitive remediation program for the treatment of behavioral problems in children with intellectual disability: the «COGNITUS & MOI» study protocol for a randomized controlled trial.

Autor: Favre E; GenoPsy, Reference center for rare diseases with psychiatric symptoms, Centre Hospitalier le Vinatier and EDR-Psy team (CNRS UMR 5229 & Lyon 1 University), 69678 BRON Cedex Lyon, Lyon, France. emilie.favre@ch-le-vinatier.fr., Peyroux E; GenoPsy, Reference center for rare diseases with psychiatric symptoms, Centre Hospitalier le Vinatier and EDR-Psy team (CNRS UMR 5229 & Lyon 1 University), 69678 BRON Cedex Lyon, Lyon, France., Babinet MN; GenoPsy, Reference center for rare diseases with psychiatric symptoms, Centre Hospitalier le Vinatier and EDR-Psy team (CNRS UMR 5229 & Lyon 1 University), 69678 BRON Cedex Lyon, Lyon, France., Poisson A; GenoPsy, Reference center for rare diseases with psychiatric symptoms, Centre Hospitalier le Vinatier and EDR-Psy team (CNRS UMR 5229 & Lyon 1 University), 69678 BRON Cedex Lyon, Lyon, France., Demily C; GenoPsy, Reference center for rare diseases with psychiatric symptoms, Centre Hospitalier le Vinatier and EDR-Psy team (CNRS UMR 5229 & Lyon 1 University), 69678 BRON Cedex Lyon, Lyon, France.; Faculty of Medicine 'Lyon Sud Charles Meyrieux', Lyon 1 University, Lyon, France.
Jazyk: angličtina
Zdroj: BMC psychiatry [BMC Psychiatry] 2018 Jul 20; Vol. 18 (1), pp. 235. Date of Electronic Publication: 2018 Jul 20.
DOI: 10.1186/s12888-018-1810-z
Abstrakt: Background: Comorbid psychiatric disorders are frequent in children with intellectual disability (ID). Given the limitations of drugs treatments, cognitive remediation could be a promising tool to reduce these challenging behaviors but evidence is still scarce. Our group recently developed the «COGNITUS & MOI» program that is designed to train the attentional and visuospatial skills in children with ID. This study investigates the efficiency of the «COGNITUS & MOI» program in this condition.
Methods: Children (age: 6.00-13.11) with mild to moderate ID and behavioral problems, will benefit from a therapy during a 16 week randomized controlled trial. One group will be randomly treated with the «COGNITUS & MOI» program and the other with a motor skill and video viewing intervention. All participants will undergo a behavioral, functional and neurocognitive assessment at baseline, post-intervention, and 6-month follow-up. Primary outcome will be the change from the baseline of the score on the "hyperactivity - noncompliance" subscale of the Aberrant Behavior Checklist.
Discussion: If the results are conclusive, the «COGNITUS & MOI» program could be added to the therapeutic arsenal against challenging behavior in children with ID.
Trial Registration: ClinicalTrials NCT02797418 . Date registered: 8th of June 2016.
Databáze: MEDLINE
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