Pemphigus Vulgaris in the Mouth and Esophageal Mucosa.

Autor: de Macedo AG; Santa Casa de Misericórdia de Piumhi, Piumhi, Brazil., Bertges ER; Hospital Therezinha de Jesus, Faculty of Medical Sciences and Health of Juiz de Fora, Juiz de Fora, Brazil., Bertges LC; Hospital Therezinha de Jesus, Faculty of Medical Sciences and Health of Juiz de Fora, Juiz de Fora, Brazil., Mendes RA; Hospital Therezinha de Jesus, Faculty of Medical Sciences and Health of Juiz de Fora, Juiz de Fora, Brazil., Bertges TABS; Hospital Therezinha de Jesus, Faculty of Medical Sciences and Health of Juiz de Fora, Juiz de Fora, Brazil., Bertges KR; Stricto Sensu Postgraduate in Health, Federal University of Juiz de Fora, Juiz de Fora, Brazil., Aarestrup FM; Stricto Sensu Postgraduate in Health, Federal University of Juiz de Fora, Juiz de Fora, Brazil.
Jazyk: angličtina
Zdroj: Case reports in gastroenterology [Case Rep Gastroenterol] 2018 Jun 15; Vol. 12 (2), pp. 260-265. Date of Electronic Publication: 2018 Jun 15 (Print Publication: 2018).
DOI: 10.1159/000489299
Abstrakt: Pemphigus vulgaris (PV) is a chronic autoimmune mucocutaneous disease. In most cases, the initial manifestation occurs in the mouth as multiple ulcerations preceded by blisters that rupture and later spread to other mucous membranes and the skin. Esophageal impairment is rare. We report a case of PV with esophageal involvement in a 53-year-old woman who sought medical care, complaining of diffuse painful lesions in the oral cavity for approximately 1 month, with no improvement with nystatin. Upper digestive endoscopy (UDE) was performed with findings of vesiculobullous lesions in the proximal and middle esophagus, which were biopsied and for which histopathology confirmed PV in the esophageal mucosa. We draw attention to UDE as important for the diagnosis, and it should be indicated in patients with vesiculobullous lesions of the mouth, especially if there are esophageal complaints.
Databáze: MEDLINE