Determining optimal poststroke exercise: Study protocol for a randomized controlled trial investigating therapeutic intensity and dose on functional recovery during stroke inpatient rehabilitation.

Autor:	Klassen TD; 1 Rehabilitation Sciences Graduate Program, Department of Physical Therapy, University of British Columbia, Vancouver, Canada.; 2 Rehabilitation Research Program, Vancouver Coastal Health Research Institute, Vancouver, Canada., Dukelow SP; 3 Department of Clinical Neurosciences and Hotchkiss Brain Institute, Cumming School of Medicine, University of Calgary, Calgary, Canada., Bayley MT; 4 Division of Physical Medicine and Rehabilitation, University of Toronto, Toronto, Canada., Benavente O; 5 Division of Neurology, University of British Columbia, Vancouver, Canada., Hill MD; 3 Department of Clinical Neurosciences and Hotchkiss Brain Institute, Cumming School of Medicine, University of Calgary, Calgary, Canada.; 6 Department of Community Health Sciences, Department of Medicine, Department of Radiology, Cumming School of Medicine, University of Calgary, Calgary, Canada., Krassioukov A; 7 Division of Physical Medicine and Rehabilitation, University of British Columbia, Vancouver, Canada.; 8 International Collaboration on Repair Discovery (ICORD), Faculty of Medicine, University of British Columbia, Vancouver, Canada., Liu-Ambrose T; 9 Department of Physical Therapy, University of British Columbia, Vancouver, Canada.; 10 Aging, Mobility and Cognitive Neuroscience Laboratory, University of British Columbia, Vancouver, Canada., Pooyania S; 11 Division of Physical Medicine and Rehabilitation, University of Manitoba, Winnipeg, Canada., Poulin MJ; 3 Department of Clinical Neurosciences and Hotchkiss Brain Institute, Cumming School of Medicine, University of Calgary, Calgary, Canada.; 12 Department of Physiology & Pharmacology, Cumming School of Medicine, University of Calgary, Calgary, Canada.; 15 O'Brien Institute for Public Health, Cumming School of Medicine, University of Calgary, Calgary, Canada., Yao J; 2 Rehabilitation Research Program, Vancouver Coastal Health Research Institute, Vancouver, Canada.; 7 Division of Physical Medicine and Rehabilitation, University of British Columbia, Vancouver, Canada., Eng JJ; 2 Rehabilitation Research Program, Vancouver Coastal Health Research Institute, Vancouver, Canada.; 9 Department of Physical Therapy, University of British Columbia, Vancouver, Canada.
Jazyk:	angličtina
Zdroj:	International journal of stroke : official journal of the International Stroke Society [Int J Stroke] 2019 Jan; Vol. 14 (1), pp. 80-86. Date of Electronic Publication: 2018 Jul 16.
DOI:	10.1177/1747493018785064
Abstrakt:	Rationale: A top priority in stroke rehabilitation research is determining the appropriate exercise dose to optimize recovery. Although more intensive rehabilitation very early after stroke may be deleterious to recovery, inpatient rehabilitation, occurring after acute care, may be a more appropriate setting to assess therapeutic dose on neurological recovery. Hypothesis: Individuals receiving higher intensity and dose exercise programs will yield greater improvements in walking ability over usual inpatient physical therapy care. Methods and Design: Seventy-five individuals across seven inpatient rehabilitation sites in Canada will be randomized into one of three treatment programs, each 5 days/week, for four weeks and monitored for exertion (heart rate) and repetitions (step count). Study Outcomes: The primary outcome measure is the 6 min walk and secondary outcomes include functional independence, cognitive, and quality-of-life measures. Outcome data will be assessed at four time points. Summary: This trial will contribute to our knowledge of the therapeutic intensity and dose necessary to maximize functional recovery at a very important stage of rehabilitation and neural recovery poststroke.
Databáze:	MEDLINE
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