Chronic mild hypoxia increases expression of laminins 111 and 411 and the laminin receptor α6β1 integrin at the blood-brain barrier.
Autor: | Halder SK; Department of Molecular Medicine, The Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, CA 92037, United States. Electronic address: skhalder@scripps.edu., Kant R; Department of Molecular Medicine, The Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, CA 92037, United States. Electronic address: ravin@scripps.edu., Milner R; Department of Molecular Medicine, The Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, CA 92037, United States. Electronic address: rmilner@scripps.edu. |
---|---|
Jazyk: | angličtina |
Zdroj: | Brain research [Brain Res] 2018 Dec 01; Vol. 1700, pp. 78-85. Date of Electronic Publication: 2018 Jul 10. |
DOI: | 10.1016/j.brainres.2018.07.012 |
Abstrakt: | The laminin family of glycoproteins are major constituents of the basal lamina of blood vessels, and play a fundamental role in promoting endothelial differentiation and blood-brain barrier (BBB) stability. Chronic mild hypoxia (CMH), in which mice are exposed to 8% O (Copyright © 2018 Elsevier B.V. All rights reserved.) |
Databáze: | MEDLINE |
Externí odkaz: |