Breast mass characterization using shear wave elastography and ultrasound.

Autor: Hari S; Department of Radiology, All India Institute of Medical Sciences, 110029 New Delhi, India., Paul SB; Department of Radiology, All India Institute of Medical Sciences, 110029 New Delhi, India. Electronic address: shashi.aiims@gmail.com., Vidyasagar R; Department of Radiology, All India Institute of Medical Sciences, 110029 New Delhi, India., Dhamija E; Department of Radiology, All India Institute of Medical Sciences, 110029 New Delhi, India., Adarsh AD; Department of Radiology, All India Institute of Medical Sciences, 110029 New Delhi, India., Thulkar S; Department of Radiology, All India Institute of Medical Sciences, 110029 New Delhi, India., Mathur S; Departments of Pathology, All India Institute of Medical Sciences, 110029 New Delhi, India., Sreenivas V; Departments of Biostatistics, All India Institute of Medical Sciences, 110029 New Delhi, India., Sharma S; Department of Radiology, All India Institute of Medical Sciences, 110029 New Delhi, India., Srivastava A; Departments of Surgery, All India Institute of Medical Sciences, 110029 New Delhi, India., Seenu V; Departments of Surgery, All India Institute of Medical Sciences, 110029 New Delhi, India., Prashad R; Departments of Surgery, All India Institute of Medical Sciences, 110029 New Delhi, India.
Jazyk: angličtina
Zdroj: Diagnostic and interventional imaging [Diagn Interv Imaging] 2018 Nov; Vol. 99 (11), pp. 699-707. Date of Electronic Publication: 2018 Jul 10.
DOI: 10.1016/j.diii.2018.06.002
Abstrakt: Purpose: To evaluate the role of SWE in characterizing breast masses and ascertain whether additional use of SWE to ultrasound for evaluating BI-RADS 3 and 4a masses could help reduce long-term follow-up and unnecessary biopsies of these suspicious breast masses.
Materials and Methods: This prospective, cross-sectional study was performed between June 2013 and November 2014. All enrolled patients underwent clinical breast examination, ultrasound, SWE and ultrasound-guided core biopsy of the breast mass. Breast Imaging Reporting and Data System (BI-RAD) categories were assigned to breast masses. For qualitative and quantitative variables of SWE, cut-off values for differentiation between benign and malignant breast masses were estimated. Modified BIRADS' (up/downgrading of BIRADS category) was done for BI-RADS 3/4a masses by combining individual SWE parameters and ultrasound findings. Sensitivity, specificity, positive and negative predictive value of modified BI-RADS' and ultrasound BI-RADS were compared.
Results: A total of 119 women (mean age, 42.3±13.6 [SD] years; range: 13-87 years) with a single breast mass each were enrolled. Histopathologically, 57/119 (48%) breast masses were benign and 62 (52%) were malignant. On ultrasound, 42 breast masses were BI-RADS3 and 77 were BI-RADS 4 (4a, n=10; 4b, n=24; 4c, n=43) leading to 96.8% sensitivity and 70.2% specificity. On SWE, benign breast masses were oval/round, homogenous/reasonably homogenous, blue/green with lower elasticity values and malignant breast masses were irregular, inhomogeneous, red/orange with high elasticity values. On modified BI-RADS' using E-color and E-mean/E-max, specificity improved to 78.9% and 75.4% respectively.
Conclusion: Addition of SWE to ultrasound improves characterization of BI-RADS 3 and 4a masses. E-max, E-mean and E-color are the most useful SWE parameters to differentiate between malignant and benign breast masses.
(Copyright © 2018 Soci showét showé françaises de radiologie. Published by Elsevier Masson SAS. All rights reserved.)
Databáze: MEDLINE
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