A novel device for intracolonoscopy cleansing of inadequately prepared colonoscopy patients: a feasibility study.
| Autor: | van Keulen KE; Department of Gastroenterology and Hepatology, Radboud University Medical Center, Nijmegen, the Netherlands., Neumann H; Department of Gastroenterology and Hepatology, University of Mainz, Mainz, Germany., Schattenberg JM; Department of Gastroenterology and Hepatology, University of Mainz, Mainz, Germany., van Esch AAJ; Department of Gastroenterology and Hepatology, Radboud University Medical Center, Nijmegen, the Netherlands., Kievit W; Radboud Institute for Health Sciences, Radboud University Medical Center, Nijmegen, the Netherlands., Spaander MCW; Department of Gastroenterology and Hepatology, Erasmus Medical Center, Rotterdam, the Netherlands., Siersema PD; Department of Gastroenterology and Hepatology, Radboud University Medical Center, Nijmegen, the Netherlands. |
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| Jazyk: | angličtina |
| Zdroj: | Endoscopy [Endoscopy] 2019 Jan; Vol. 51 (1), pp. 85-92. Date of Electronic Publication: 2018 Jul 11. |
| DOI: | 10.1055/a-0632-1927 |
| Abstrakt: | Background: The importance of high quality preprocedural bowel preparation is widely acknowledged, but suboptimal bowel cleansing still occurs in up to 20 % of all colonoscopy patients. The aim of this study was to evaluate the performance of a novel intraprocedural cleaning device for cleaning poorly prepared colons. Methods: This multicenter feasibility study included patients aged 18 - 75 years who were referred for colonoscopy. Intraprocedural cleaning was performed in patients after a limited preprocedural bowel preparation regimen (2 days of dietary restrictions and 2 × 10 mg bisacodyl). The primary outcome was the proportion of adequately prepared patients (Boston Bowel Preparation scale [BBPS] ≥ 2 in each segment) before and after segmental washing with the new device. Secondary outcomes included: cecal intubation rate, procedure time, system usability, patient satisfaction, and safety. Results: 47 patients (42.6 % male), with a median age of 61 years (interquartile range [IQR] 46 - 67 years), were included at three clinical sites. Cecal intubation was achieved in 46/47 patients (97.9 %). The cleaning device significantly improved the proportion of patients with adequate bowel cleansing (from 19.1 % to 97.9 %; P < 0.001) and median BBPS score (from 3.0 [IQR 0.0 - 5.0] to 9.0 [IQR 8.0 - 9.0]). Median cecal intubation time and total procedure time were 16.5 minutes (IQR 9.0-28.3) and 34.0 minutes (IQR 25.0 - 42.8), respectively. Physicians were satisfied with the ease of use of the device and it was well tolerated by patients. No severe adverse events occurred during the study period. Conclusions: This feasibility study suggests that the intraprocedural cleaning device appears to be safe and effective in cleaning poorly prepared colons to an adequate level, allowing a thorough colorectal examination. Competing Interests: The study was sponsored by Motus GI. The sponsor did not have a role in data collection, data analysis or interpretation, writing of the manuscript or decision to submit for publication. (© Georg Thieme Verlag KG Stuttgart · New York.) |
| Databáze: | MEDLINE |
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