Associations of vitamin D status and metabolic dyslipidemia and hypertriglyceridemic waist phenotype in apparently healthy adults.

Autor: Rashidbeygi E; Department of Community Nutrition, School of Nutrition and Food Science, Tehran University of Medical Sciences (TUMS), Tehran, Iran., Rahimi MH; Department of Community Nutrition, School of Nutrition and Food Science, Tehran University of Medical Sciences (TUMS), Tehran, Iran., Mollahosseini M; Department of Community Nutrition, School of Nutrition and Food Science, Tehran University of Medical Sciences (TUMS), Tehran, Iran., Yekaninejad MS; Department of Epidemiology and Biostatistics, School of Public Health, Tehran University of Medical Sciences (TUMS), Tehran, Iran., Imani H; Department of Clinical Nutrition, School of Nutritional Sciences and Dietetics, Tehran University of Medical Sciences (TUMS), Tehran, Iran., Maghbooli Z; MS Research Center, Neurosciences Institute of Tehran University of Medical Sciences (TUMS), Tehran, Iran., Mirzaei K; Department of Community Nutrition, School of Nutrition and Food Science, Tehran University of Medical Sciences (TUMS), Tehran, Iran. Electronic address: mirzaei_kh@tums.ac.ir.
Jazyk: angličtina
Zdroj: Diabetes & metabolic syndrome [Diabetes Metab Syndr] 2018 Nov; Vol. 12 (6), pp. 985-990. Date of Electronic Publication: 2018 Jun 28.
DOI: 10.1016/j.dsx.2018.06.010
Abstrakt: Background: Recent studies have shown that Vitamin D deficiency is very common globally. Vitamin D deficiency is associated with lipid metabolism. A relationship between vitamin D levels and waist circumference (WC) has been observed. The purpose of this study is to evaluate the relationship between vitamin D status and metabolic dyslipidemia and the hypertriglyceridemic waist phenotype.
Methods: This cross-sectional study was conducted on 265 healthy Tehran adults. Hypertriglyceridemic waist phenotype (HTGWP) was described as serum triacylglycerol concentrations >150 mg/dL and concurrent WC > 88 cm (women) and >102 cm (men). Dyslipidemia was defined as: 1) TG level of >150 mg/dL 2) HDL > 40 mg/dL for men or >50 mg/dL for women, as has been previously described.
Results: Current study's results demonstrated that HTGWP was significantly associated with weight, age, WC, hip, fat percent, TG, lipid profile, ALT and BMI. We found 77% reduction in the chances of developing metabolic dyslipidemia in suficient satus of vitamin D in compare to deficiency, although the significancy was mariginal, OR: 0.33, 95% CI of 0.09 to 1.21, P = 0.09. However, our results revealed that vitamin D deficiency, compared with normal status, can increase the risk of phenotype 1 (high TG/high WC); OR: 3.86 and 95% CI from 0.86 to 0.99, p for trend = 0.05.
Conclusions: Significant associations were found between vitamin D status and HTGWP. In addition, there was a relationship between vitamin D and lipid profiles. There is a direct correlation between TG and waist circumference in insulin resistance in healthy Tehran adults.
(Copyright © 2018 Diabetes India. All rights reserved.)
Databáze: MEDLINE
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