Valvular involvement in granulomatosis with polyangiitis: Case report and systematic review of literature.

Autor: Al-Habbaa A; Faculty of Medicine, Cardiology Department, Al-Azhar University, Cairo, Egypt., Rawla P; Department of Internal Medicine, SOVAH Heath, Martinsville, VA, USA., Morra ME; Faculty of Medicine, Al-Azhar University, Cairo, Egypt., Abotaha AA; Faculty of Medicine, Internal Medicine Department, Al-Azhar University, Cairo, Egypt., Sakr EE; Faculty of Medicine, Menoufia University, Menoufia, Egypt., Abdo Shehata MA; Faculty of Medicine, Alexandria University, Alexandria, Egypt., Shahin KM; Faculty of Medicine, Alexandria University, Alexandria, Egypt., Abdel Mageed S; Faculty of Medicine, Internal Medicine Department, Tanta University, Tanta, Egypt., Huy NT; Department of Clinical Product Development, Institute of Tropical Medicine (NEKKEN), Leading Graduate School Program, and Graduate School of Biomedical Sciences, Nagasaki University, Nagasaki, Japan.
Jazyk: angličtina
Zdroj: Echocardiography (Mount Kisco, N.Y.) [Echocardiography] 2018 Sep; Vol. 35 (9), pp. 1456-1463. Date of Electronic Publication: 2018 Jul 08.
DOI: 10.1111/echo.14094
Abstrakt: Background: Granulomatosis with polyangiitis (GPA) is a systemic inflammatory condition; however, patients with GPA rarely experience endocardial valve lesions.
Methods: We report a GPA case with tricuspid valve destruction together with a systematic review to highlight the characteristics of all previously reported GPA cases with valvular involvement.
Results: Among 36 cases included, the aortic valve was involved in 15 (41.7%) cases while the mitral valve was involved in 9 (25%) subjects. Combined lesion of both aortic and mitral valves was reported in 9 (25%) patients.
Conclusion: We recommend routine echocardiography examination to rule out any cardiac valve lesion once GPA is suspected.
(© 2018 Wiley Periodicals, Inc.)
Databáze: MEDLINE
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