| Autor: |
Sharifi-Rad J; Phytochemistry Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran., Tayeboon GS; Department of Biology, Payamenoor University, PO BOX19395-3697, Tehran, Iran., Niknam F; Department of Biochemistry, Faculty of Medicine, Hormozgan University of Medical Sciences, Bandar Abbas, Iran., Sharifi-Rad M; Department of Range and Watershed Management, Faculty of Natural Resources, University of Zabol, Zabol, Iran., Mohajeri M; Phytochemistry Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran., Salehi B; Medical Ethics and Law Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran., Iriti M; Department of Agricultural and Environmental Sciences, Milan State University, 20133 Milan, Italy., Sharifi-Rad M; Department of Medical Parasitology, Zabol University of Medical Sciences, 61663335 Zabol, Iran. |
| Abstrakt: |
Veronica persica (Persian speedwell) is a flowering plant local to Eurasia. In this study, several analyses were done to discover the antimicrobial and scolicidal activities and acetyl cholinesterase (AChE), tyrosinase (TYR), lipoxygenase (LOX), and xanthine oxidase (XO) inhibitory activities of V. persica extract. The results presented that B. subtilis was the most susceptible to the extract (MIC = 40.3 μg/mL), while P. aeruginosa was the most resistant strain (MIC = 250.9 μg/mL) among all bacteria evaluated. The extracts demonstrated significant activity versus E. granulosus (P < 0.5) with dose-dependent inhibitions of the protoscolices. The analyzed plant extract exhibited a high AChE and TYR inhibitory activity 55.3% and 52.7% (at the highest utilized dose - 3 mg/mL), respectively. The extract also showed high anti-inflammatory activities in analyses tested. Our research proposed that extract of this plant could be promising to the human health, markedly in the infectious, neurodegenerative and inflammatory disorders. |
