| Autor: |
Nageen B; Faculty of Life Sciences, Department of Zoology, Government College University Faisalabad, Faisalabad 38000, Pakistan., Sarfraz I; Faculty of Life Sciences, Department of Zoology, Government College University Faisalabad, Faisalabad 38000, Pakistan., Rasul A; Faculty of Life Sciences, Department of Zoology, Government College University Faisalabad, Faisalabad 38000, Pakistan., Hussain G; Faculty of Life Sciences, Department of Physiology, Government College University Faisalabad, Faisalabad 38000, Pakistan., Rukhsar F; Faculty of Life Sciences, Department of Zoology, Government College University Faisalabad, Faisalabad 38000, Pakistan., Irshad S; Faculty of Life Sciences, Department of Zoology, Government College University Faisalabad (Sub-campus Layyah), Layyah 31200, Pakistan., Riaz A; Faculty of Life Sciences, Department of Zoology, Government College University Faisalabad, Faisalabad 38000, Pakistan., Selamoglu Z; Faculty of Medicine, Department of Medical Biology, Nigde Ömer Halisdemir University, Nigde, Campus 51240, Turkey., Ali M; Faculty of Life Sciences, Department of Zoology, Government College University Faisalabad, Faisalabad 38000, Pakistan. |
| Abstrakt: |
Eupatilin (5,7-dihydroxy-3',4',6-trimethoxyflavone) is a pharmacologically active flavone which has been isolated from a variety of medicinal plants. Eupatilin is known to possess various pharmacological properties such as anti-cancer, anti-oxidant, and anti-inflammatory. It is speculated that eupatilin could be subjected to structural optimization for the synthesis of derivative analogs to reinforce its efficacy, to minimize toxicity, and to optimize absorption profiles, which will ultimately lead towards potent drug candidates. Although, reported data acclaim multiple pharmacological activities of eupatilin but further experimentations on its molecular mechanism of action are yet mandatory to elucidate full spectrum of its pharmacological activities. |
