Sensorineural Deafness Following Tacrolimus Use.

Autor: Lakshmi BS; From the Department of Nephrology, Sri Venkateswar Institute of Medical Sciences, Tirupati, India., Vidya B, Reddy MHK, Kumar ACV, Ram R, Kumar VS
Jazyk: angličtina
Zdroj: Experimental and clinical transplantation : official journal of the Middle East Society for Organ Transplantation [Exp Clin Transplant] 2020 Feb; Vol. 18 (1), pp. 110-111. Date of Electronic Publication: 2018 Jul 02.
DOI: 10.6002/ect.2017.0114
Abstrakt: Early trials of tacrolimus in renal transplant recipients have not revealed hearing loss as an adverse effect. Here, we present a case report and a review of the literature of deafness after tacrolimus use. The review of the literature and our experience suggested that the possible reason for hearing loss could be due to an initiation of a sudden spike in the tacrolimus serum level, which was later worsened by its cumulative toxic effect.
Databáze: MEDLINE