Bioreactions at the tissue/hydroxyapatite interface.

Autor: van Blitterswijk CA, Grote JJ, Kuÿpers W, Blok-van Hoek CJ, Daems WT
Jazyk: angličtina
Zdroj: Biomaterials [Biomaterials] 1985 Jul; Vol. 6 (4), pp. 243-51.
DOI: 10.1016/0142-9612(85)90020-1
Abstrakt: The events at the hydroxyapatite implant material/tissue interface in the rat middle ear were studied by light microscopy, autoradiography, morphometry, transmission electron microscopy (TEM), scanning electron microscopy (SEM), and X-ray microanalysis. Deposition of calcium, partially in the form of calcium phosphate, was found at the interface. Resorption of the implant material occurred as the result of mono- and multinuclear phagocyte activity. Resorption decreased 6 mnth after the operation, possibly due to the decreasing number of phagocytes at the interface and the increasing amount of bone in the macropores.
Databáze: MEDLINE