Apocrine Encapsulated Papillary Carcinoma of the Breast: The First Reported Case with an Infiltrative Component.

Autor: Kővári B; Department of Pathology, University of Szeged, Szeged, Hungary., Ormándi K; Department of Radiology, University of Szeged, Szeged, Hungary.; Affidea Diagnostics-Szeged, Szeged, Hungary., Simonka Z; Department of Surgery, University of Szeged, Szeged, Hungary., Vörös A; Department of Pathology, University of Szeged, Szeged, Hungary., Cserni G; Department of Pathology, University of Szeged, Szeged, Hungary.; Department of Pathology, Bács-Kiskun County Teaching Hospital, Kecskemét, Hungary.
Jazyk: angličtina
Zdroj: Journal of breast cancer [J Breast Cancer] 2018 Jun; Vol. 21 (2), pp. 227-230. Date of Electronic Publication: 2018 Jun 20.
DOI: 10.4048/jbc.2018.21.2.227
Abstrakt: Apocrine encapsulated papillary carcinoma (EPC) of the breast is a rare neoplasm, and only 10 cases have been reported in the literature to date. Although EPC by definition lacks a peripheral myoepithelial layer, all previously published apocrine EPC cases were clinically indolent and lacked a conventional invasive component. Herein, we report the 11th case of apocrine EPC, which had a conventional invasive carcinoma component and provides evidence of the malignant potential of this entity. We postulate that apocrine EPC is most likely a morphological variant of conventional EPC, with the same unpredictable malignant potential as non-apocrine cases.
Competing Interests: CONFLICT OF INTEREST: The authors declare that they have no competing interests.
Databáze: MEDLINE