Role of cytoreductive surgery and hyperthermic intraperitoneal chemotherapy in the treatment of gastric cancer.

Autor:	López-Basave HN; Department of Gastrointestinal Tumors, National Cancer Institute of Mexico. Mexico., Quiroz-Sandoval OA; Department of Gastrointestinal Tumors, National Cancer Institute of Mexico. Mexico., Padilla-Rosciano AE; Department of Gastrointestinal Tumors, National Cancer Institute of Mexico. Mexico., León-Takahashi AM; Department of Gastrointestinal Tumors, National Cancer Institute of Mexico. Mexico., Miranda-Devora G; Department of Gastrointestinal Tumors, National Cancer Institute of Mexico. Mexico., Arrollo-Monroy A; Department of General Surgery, 'Dr. Antonio González Guevara' Hospital. Mexico.
Jazyk:	angličtina
Zdroj:	Cirugia y cirujanos [Cir Cir] 2018; Vol. 86 (3), pp. 277-284.
DOI:	10.24875/CIRU.M18000040
Abstrakt:	Patients with peritoneal carcinomatosis (PC) of gastric origin have a poor prognosis of life with an average survival of 1-3 months. Systemic chemotherapy has improved the survival of those patients with gastric metastatic cancer at 7-10 months. However, this benefit could not be reproduced in those patients with PC. The current literature for the use of hyperthermic intraperitoneal chemotherapy (HIPEC) for gastric PC has significant variation related to patient selection, treatment intent (palliative vs. attempt at curative treatment), surgical technique, intraperitoneal chemotherapy agent utilized, and systemic chemotherapy administered adjuvantly. From the perspective of patient selection for cytoreduction and HIPEC, patients with extensive PC are not candidates. In addition, unresectable location would make a patient a poor candidate for cytoreduction and HIPEC. Optimally, those with positive peritoneal cytology alone could benefit most. However, the role of cytoreductive surgery and HIPEC in patients with PC of gastric origin has not yet been clarified. (Copyright: © 2018 SecretarÍa de Salud.)
Databáze:	MEDLINE
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