Prevalence of metabolic syndrome in stroke patients: a prospective multicenter study in Japan.

Autor: Takahashi T; Emergency and Critical Care Center of Kumamoto Medical Center National Hospital Organization Kumamoto Japan., Harada M; Emergency and Critical Care Center of Kumamoto Medical Center National Hospital Organization Kumamoto Japan., Kikuno T; Emergency and Critical Care Center of Tokyo Medical Center National Hospital Organization Tokyo Japan., Ujihara M; Metabolic Medicine of Yokohama Medical Center National Hospital Organization Kanagawa Japan., Sadamitsu D; Emergency and Critical Care Center of Osaka Medical Center National Hospital Organization Osaka Japan., Manabe Y; Neurology of Okayama Medical Center National Hospital Organization Okayama Japan., Yasaka M; Neurology of Kyusyu Medical Center National Hospital Organization Fukuoka Japan., Takayama H; Emergency and Critical Care Center of Nagasaki Medical Center National Hospital Organization Nagasaki Japan., Kobori S; Metabolic Medicine of Miyazaki Hospital National Hospital Organization Miyazaki Japan., Araki E; Department of Metabolic Medicine, Faculty of Life Sciences Kumamoto University Kumamoto Japan.
Jazyk: angličtina
Zdroj: Acute medicine & surgery [Acute Med Surg] 2013 Oct 18; Vol. 1 (1), pp. 17-22. Date of Electronic Publication: 2013 Oct 18 (Print Publication: 2014).
DOI: 10.1002/ams2.1
Abstrakt: Aims: The fact that Metabolic Syndrome (MetS) increases the risk of atherosclerosis has been epidemiologically studied and proven; however, a prospective study on the prevalence of MetS in stroke patients has never been conducted because of the difficulty in diagnosis under critical illness in the acute phase. Therefore, we conducted a prospective multicenter study to investigate the prevalence of MetS in stroke patients with modified diagnostic criteria for MetS.
Methods: Stroke patients admitted in the seven participating Emergency and Critical Care Centers within the two years from April 2007 were registered in this study as a prospective multicenter study. Inclusion criteria were 50 to 89 year-old stroke patients who presented within three days from the onset of symptoms. A total of 992 subjects were classified according to the stroke type and the prevalence of MetS and the associated risk factors were investigated. The participants in a medical checkup without any history of a stroke were enrolled as the control group, and compared between the two groups.
Results: The prevalence of MetS as well as hyperglycemia and dyslipidemia in the infarction group was significantly higher than that in the non-stroke group. While the hemorrhage group showed no significant difference in the prevalence of MetS, only hypertension was significantly high. According to a subtype analysis, there is a significant correlation between waist circumference increment of the stroke patients and the prevalence of the risk factors of hypertension, hyperglycemia and dyslipidemia.
Conclusions: Different risk factors are significantly related to the type of stroke.
Databáze: MEDLINE