Expression of Galectins-1 and Galectin-3 in Stomach and Colorectal Cancer with Tissue Eosinophilia.

Autor: Kolobovnikova YV; Siberian State Medical University, Ministry of Health of the Russian Federation, Tomsk, Russia. kolobovnikova.julia@mail.ru., Dmitrieva AI; Siberian State Medical University, Ministry of Health of the Russian Federation, Tomsk, Russia.; Tomsk Regional Oncological Health Center, Tomsk, Russia., Yankovich KI; Siberian State Medical University, Ministry of Health of the Russian Federation, Tomsk, Russia.; Tomsk Regional Oncological Health Center, Tomsk, Russia., Vasil'eva OA; Siberian State Medical University, Ministry of Health of the Russian Federation, Tomsk, Russia., Purlik IL; Siberian State Medical University, Ministry of Health of the Russian Federation, Tomsk, Russia.; Tomsk Regional Oncological Health Center, Tomsk, Russia., Poletika VS; Siberian State Medical University, Ministry of Health of the Russian Federation, Tomsk, Russia., Novitskii VV; Siberian State Medical University, Ministry of Health of the Russian Federation, Tomsk, Russia., Urazova OI; Siberian State Medical University, Ministry of Health of the Russian Federation, Tomsk, Russia.
Jazyk: angličtina
Zdroj: Bulletin of experimental biology and medicine [Bull Exp Biol Med] 2018 Jun; Vol. 165 (2), pp. 256-258. Date of Electronic Publication: 2018 Jun 20.
DOI: 10.1007/s10517-018-4142-6
Abstrakt: We analyzed the expression of galectin-1 and galectin-3 in tumor tissue in stomach and colorectal cancer with and without tissue eosinophilia. Low expression of galectin-3 was detected in all patients with malignant gastrointestinal tumors irrespective of the presence of eosinophilia. Low expression of galectin-1 was detected only in patients with gastrointestinal cancer associated with eosinophilia. Association of galectin-1 expression with eosinophilic infiltration of the tumor tissue in stomach and colorectal cancer was detected.
Databáze: MEDLINE
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