[Reference values of neonatal erythrocyte and leukocyte count in Bamako, Mali].

Autor: Diallo DA; Centre de Recherche et de Lutte contre la Drépanocytose, 03 BP: 186 Point G, Bamako, Mali.; Service d'hématologie oncologie médicale du CHU du Point G, Bamako, Mali., Diawara F; Centre de santé de référence de la commune V, Bamako, Mali., Guindo A; Centre de Recherche et de Lutte contre la Drépanocytose, 03 BP: 186 Point G, Bamako, Mali., Touré M; Centre de santé de référence de la commune IV, Bamako, Mali., Traoré M; Centre de santé de référence de la commune V, Bamako, Mali., Fofana AT; Centre de santé de Hamdallaye, Bamako, Mali., Dembélé AK; Service d'hématologie oncologie médicale du CHU du Point G, Bamako, Mali., Guindo A; Laboratoire clinique du MRTC/ICER, FMPOS, Université de Bamako, Mali., Diallo YL; Service d'hématologie oncologie médicale du CHU du Point G, Bamako, Mali., Diallo O; Centre hospitalier Mère/Enfant le Luxembourg, Bamako, Mali., Baraika AM; Centre de Recherche et de Lutte contre la Drépanocytose, 03 BP: 186 Point G, Bamako, Mali., Dolo AI; Service de gynécologie-obstétrique du CHU Gabriel Touré, Bamako, Mali.
Jazyk: francouzština
Zdroj: Le Mali medical [Mali Med] 2013; Vol. 28 (1), pp. 36-43.
Abstrakt: Reference values for blood cell count are not established at birth in Mali. This study aimed to determine reference values for erythrocyte and leukocyte at birth in Bamako. Blood was collected from the umbilical cord immediately following its clamping and studied for complete blood cell count in 481 newborns with a birth weight > 2500g, Apgar score ≤ 7 at 5 or 10 minutes, without abnormal hemoglobin mutations and whose mothers were willing in Bamako, Mali. Other than the median and mean values, 2.5 and 97.5 percentiles were calculated. The findings suggest that the normal reference values following a timely clamping of the umbilical cord were (mean ± 1SD and range): RBC = 4,00 ± 0,46.1012/L (3,13 - 4,89), Hb = 14,12 ± 1,49 g/dL (11,20 - 17,00), Hct = 40,27 ± 4,71% (31,62 - 50,18), MCV = 101 ± 5 fl (91 - 112), MCHC = 35,37 ± 2,16 pg/cellule (30,70 - 39,59), MCH = 35,06 ± 0,93 g/dL (33,40 - 36,90), RDW = 17,79 ± 7,33% (15,50 - 20,39), Reticulocytes (109/L) = 133,081 ± 29,95 (66,62 - 200,86), GB (109/L) = 13,24 ± 7,23 (7,20 - 23,70), PMN (109/L) = 7,16 ± 4,70 (3,07 - 14,22), PME (109/L) = 0,28 ± 0,26 (0 - 0,98), PMB(109/L) = 0,05 ± 0,09 (0 - 0,31), Lymphocytes (109/L) = 4,49 ± 2,45 (1,96 - 9,42), Monocytes (10 9 /L) = 1,06 ± 0,73 (0,21 - 2,54), myelocytes = 1.43 ± 1.51%, erythroblasts = 4.52 ± 7.83%. It should be noted that male babies had a lower neutrophil count than female newborns. By taking into account these results when interpreting the blood cell count in Malian newborn infants, costly misdiagnoses should be considerably decreased in a population struggling with low incomes.
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Databáze: MEDLINE
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