| Autor: |
Farrell RM; Department of Obstetrics and Gynecology and Department of Bioethics, Cleveland Clinic Women's Health Institute.; Department of Bioethics, Cleveland Clinic.; Genomic Medicine Institute, Cleveland Clinic Center for Personalized Genetic Healthcare., Agatisa PK; Department of Bioethics, Cleveland Clinic., Mercer M; Department of Bioethics, Cleveland Clinic., Coleridge MB; Genomic Medicine Institute, Cleveland Clinic Center for Personalized Genetic Healthcare. |
| Jazyk: |
angličtina |
| Zdroj: |
Reproductive biomedicine & society online [Reprod Biomed Soc Online] 2016 Mar 10; Vol. 1 (2), pp. 88-97. Date of Electronic Publication: 2016 Mar 10 (Print Publication: 2015). |
| DOI: |
10.1016/j.rbms.2016.02.002 |
| Abstrakt: |
Non-invasive prenatal testing (NIPT) has been integrated into clinical care at a time when patients and healthcare providers increasingly utilize the internet to access health information. This study evaluated online direct-to-consumer information about NIPT produced by commercial laboratories accessible to both patients and healthcare providers. A coding checklist captured areas to describe content and assess concordance with clinical guidelines. We found that the information presented about NIPT is highly variable, both within a single website and broadly across all websites. Variability was noted in how NIPT is characterized, including test characteristics and indications. All laboratories offer NIPT to test for common sex chromosome aneuploidies, although there is a lack of consistency regarding the conditions offered and information provided about each. Although indicated for a subset of women at increased risk of aneuploidy, some laboratories describe the use of NIPT for all pregnant women. A subset of laboratories offers screening for microdeletions, although clinical practice guidelines do not yet recommend for general use for this indication. None of the online materials addressed the ethical issues associated with NIPT. This study highlights the need for clear, consistent, and evidence-based materials to educate patients and healthcare providers about the current and emerging applications of NIPT. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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