| Autor: |
Vivaldo JF; Autoimmune Lab, School of Medical Science, University of Campinas, Campinas, Brazil.; Graduate Program in Child and Adolescent Health, School of Medical Science, University of Campinas, Campinas, Brazil., de Amorim JC; Autoimmune Lab, School of Medical Science, University of Campinas, Campinas, Brazil.; Graduate Program in Child and Adolescent Health, School of Medical Science, University of Campinas, Campinas, Brazil., Julio PR; Autoimmune Lab, School of Medical Science, University of Campinas, Campinas, Brazil.; Graduate Program in Child and Adolescent Health, School of Medical Science, University of Campinas, Campinas, Brazil., de Oliveira RJ; Autoimmune Lab, School of Medical Science, University of Campinas, Campinas, Brazil.; Graduate Program in Child and Adolescent Health, School of Medical Science, University of Campinas, Campinas, Brazil., Appenzeller S; Autoimmune Lab, School of Medical Science, University of Campinas, Campinas, Brazil.; Rheumatology Unit, School of Medical Science, University of Campinas, Campinas, Brazil. |
| Abstrakt: |
Systemic lupus erythematosus (SLE) patients have frequently neuropsychiatric manifestations. From the first description of coma in 1875, a variety of manifestations has been described to occur in SLE. However, the lack of standardization reduced the comparability of published studies. In 1999, the American College of Rheumatology published guidelines to define neuropsychiatric nomenclature in SLE. This was the first step toward uniform diagnostic criteria. Several studies have been published since then applying the ACR criteria and frequencies of different manifestations can now be compared between cohorts. Although these criteria are diagnostic, therapeutic approach to different manifestations varies according to nature and severity of the manifestations. Herby, we will review the different definition for NPSLE published, and determine advantages and limitation. |
