One-year prognosis of non-traumatic cortical subarachnoid haemorrhage: A prospective series of 34 patients.

Autor:	Galiano Blancart RF; Servicio de Neurología, Hospital Dr. Peset, Valencia, España. Electronic address: rafa_galiano@yahoo.es., Fortea G; Servicio de Neurología, Hospital La Fe, Valencia, España., Pampliega Pérez A; Servicio de Neurología, Hospital General de Alicante, Alicante, España., Martí S; Servicio de Neurología, Hospital General de Alicante, Alicante, España., Parkhutik V; Servicio de Neurología, Hospital La Fe, Valencia, España., Sánchez Cruz AV; Servicio de Neurología, Hospital de Sagunto, Sagunto, España., Soriano C; Servicio de Neurología, Hospital General de Castellón, Castelló de la Plana, España., Geffner Sclarsky D; Servicio de Neurología, Hospital General de Castellón, Castelló de la Plana, España., Pérez Saldaña MT; Hospital de Manises, Manises, España., López Hernández N; Servicio de Neurología, Hospital General de Alicante, Alicante, España., Beltrán I; Servicio de Neurología, Hospital General de Alicante, Alicante, España., Lago Martín A; Servicio de Neurología, Hospital La Fe, Valencia, España.
Jazyk:	English; Spanish; Castilian
Zdroj:	Neurologia (Barcelona, Spain) [Neurologia (Engl Ed)] 2021 Apr; Vol. 36 (3), pp. 215-221. Date of Electronic Publication: 2018 Jun 11.
DOI:	10.1016/j.nrl.2017.12.008
Abstrakt:	Introduction: Cortical subarachnoid haemorrhage (cSAH) has multiple aetiologies. No prospective study has reported the long-term progression of the condition. The objective of this study is to describe the clinical and aetiological characteristics of patients with cSAH and to gain insight into prognosis. Methods: We performed a prospective, observational, multi-centre study. Data on clinical and radiological variables were collected; during a one-year follow-up period, we recorded data on mortality, dependence, rebleeding, and the appearance of dementia. Results: The study included 34 patients (mean age, 68.3 years; range, 27-89). The most frequent symptoms were headache and focal neurological deficits, which were frequently transient and recurrent. CT scans returned pathological findings in 28 patients (85%). Brain MRI scans were performed in 30 patients (88%), revealing acute ischaemia in 10 (29%), old haemorrhage in 7 (21%), and superficial siderosis in 2 (6%). Aetiology was identified in 26 patients (76.5%): causes were cerebral amyloid angiopathy in 8, ischaemic stroke in 5, vasculitis in 4, reversible posterior encephalopathy in 2, venous thrombosis in 2, reversible cerebral vasoconstriction syndrome in 2, carotid occlusion in 1, Marfan syndrome in 1, and meningeal carcinomatosis in 1. Three patients died during follow-up (2 due to causes related to the cause of cSAH). Three patients developed dementia, 3 had lobar haemorrhages, and one had a second cSAH. Conclusions: The most frequent causes of cSAH in our series were cerebral amyloid angiopathy, ischaemic stroke, and vasculitis. This type of haemorrhage has a worse prognosis than other non-aneurysmal cSAH. There are numerous possible causes, and prognosis depends on the aetiology. In elderly patients, intracranial haemorrhage is frequently associated with cognitive impairment. (Copyright © 2018 Sociedad Española de Neurología. Publicado por Elsevier España, S.L.U. All rights reserved.)
Databáze:	MEDLINE
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