Datasets describing the growth and molecular features of hepatocellular carcinoma patient-derived xenograft cells grown in a three-dimensional macroporous hydrogel.

Autor:	Fong ELS; Department of Biomedical Engineering, National University of Singapore, Singapore., Toh TB; Cancer Science Institute of Singapore, National University of Singapore, Singapore., Lin QXX; Cancer Science Institute of Singapore, National University of Singapore, Singapore., Liu Z; Institute of Bioengineering and Nanotechnology, Agency for Science, Technology and Research (ASTAR) Singapore., Hooi L; Cancer Science Institute of Singapore, National University of Singapore, Singapore., Rashid MBMA; Cancer Science Institute of Singapore, National University of Singapore, Singapore., Benoukraf T; Cancer Science Institute of Singapore, National University of Singapore, Singapore., Chow EK; Cancer Science Institute of Singapore, National University of Singapore, Singapore.; Department of Pharmacology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore., Huynh TH; National Cancer Center Singapore, Singapore., Yu H; Institute of Bioengineering and Nanotechnology, Agency for Science, Technology and Research (ASTAR) Singapore.; Department of Physiology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore.; Mechanobiology Institute, National University of Singapore, Singapore.; BioSyM, Singapore-MIT Alliance for Research and Technology, Singapore.; Department of Gastroenterology, Nanfang Hospital, Southern Medical University, Guangzhou, China.; NUS Graduate School of Integrative Sciences and Engineering, National University of Singapore, Singapore.
Jazyk:	angličtina
Zdroj:	Data in brief [Data Brief] 2018 Mar 17; Vol. 18, pp. 594-606. Date of Electronic Publication: 2018 Mar 17 (Print Publication: 2018).
DOI:	10.1016/j.dib.2018.03.045
Abstrakt:	This data article presents datasets associated with the research article entitled "Generation of matched patient-derived xenograft in vitro-in vivo models using 3D macroporous hydrogels for the study of liver cancer" (Fong et al., 2018) [1]. A three-dimensional macroporous sponge system was used to generate in vitro counterparts to various hepatocellular carcinoma patient-derived xenograft (HCC-PDX) lines. This article describes the viability, proliferative capacity and molecular features (genomic and transcriptomic profiles) of the cultured HCC-PDX cells. The sequencing datasets are made publicly available to enable critical or further analyzes.
Databáze:	MEDLINE
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