| Autor: |
Virk MS; Department of Pathology and Laboratory Medicine, Medstar Georgetown University Hospital, Washington, DC., Dean NP; Division of Critical Care Medicine, Children's National Medical Center, Washington, DC., Wong ECC; Division of Laboratory Medicine and Hematology, Children's National Medical Center, Washington, DC. |
| Jazyk: |
angličtina |
| Zdroj: |
Laboratory medicine [Lab Med] 2018 Oct 11; Vol. 49 (4), pp. 372-376. |
| DOI: |
10.1093/labmed/lmy025 |
| Abstrakt: |
Current chemistry analyzers measure ion concentration using ion- selective electrodes; however, may differ in the specific technology at the bedside versus the central laboratory. Instruments utilized for point-of-care testing (POCT) at the bedside use direct ion-selective electrodes, whereas central-laboratory analyzers use indirect ion-selective electrodes. Under most circumstances, these instruments will deliver the same result; however, various substances can cause interferences in one or the other. An 18-year-old Hispanic woman with a history of immune thrombocytopenic purpura (ITP) presented at Children's National Medical Center (CNMC) with a severe headache and required intravenous immunoglobulin (IVIG) therapy. Because a discrepancy developed between her point-of-care and central-laboratory sodium values, another instrument was used to retest the central-laboratory plasma specimens. The results were more in agreement with those from the point-of-care instrument and revealed a unique interference in sodium measurement related to IVIG use. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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