Primary lateral sclerosis-like picture in a patient with a remote history of anti-N-methyl-D- aspartate receptor (anti-NMDAR) antibody encephalitis.

Autor: Janmohamed M; Department of Neurology, Fiona Stanley Hospital, Perth, Western Australia, Australia., Knezevic W; Department of Neurology, Fiona Stanley Hospital, Perth, Western Australia, Australia., Needham M; Department of Neurology, Fiona Stanley Hospital, Perth, Western Australia, Australia., Salman S; Department of Clinical Immunology, Fiona Stanley Hospital, Perth, Western Australia, Australia.; Medical School, University of Western Australia, Perth, Western Australia, Australia.
Jazyk: angličtina
Zdroj: BMJ case reports [BMJ Case Rep] 2018 Jun 10; Vol. 2018. Date of Electronic Publication: 2018 Jun 10.
DOI: 10.1136/bcr-2017-224060
Abstrakt: Anti-N-methyl-D-aspartate receptor (anti-NMDAR) encephalitis is a well-recognised disorder, first fully characterised in 2007. The long-term sequelae reported thus far include relapses with typical, as well as partial aspects of the well-defined neuropsychiatric syndrome. Rarely, isolated atypical symptoms (diplopia, ataxia and tremor) have been reported as relapse phenomenon. We report a case of a patient with a remote history of likely anti-NMDAR encephalitis with the longest follow-up reported in the literature to date (22 years). The relapse presentation was of a purely upper motor neuron syndrome with a primary lateral sclerosis-like picture.
Competing Interests: Competing interests: None declared.
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Databáze: MEDLINE