Perspectives on the relation of blood pressure and cognition in the elderly.

Autor: Goshgarian C; Vascular Neurology Program, Mercy Health Hauenstein Neurosciences, 220 Cherry Street SE Room H 3037, Grand Rapids, MI 49503, United States. Electronic address: Christopher.goshgarian@mercyhealth.com., Gorelick PB; Vascular Neurology Program, Mercy Health Hauenstein Neurosciences, 220 Cherry Street SE Room H 3037, Grand Rapids, MI 49503, United States; Translational Science and Molecular Medicine, Michigan State University College of Human Medicine, MI United States. Electronic address: pgorelic@mercyhealth.com.
Jazyk: angličtina
Zdroj: Trends in cardiovascular medicine [Trends Cardiovasc Med] 2019 Jan; Vol. 29 (1), pp. 12-18. Date of Electronic Publication: 2018 Jun 02.
DOI: 10.1016/j.tcm.2018.05.011
Abstrakt: The relationship of blood pressure to cognition in the elderly is a poorly understood topic. Many questions exist such as does treatment of hypertension prevent cognitive decline, the optimal timing of intervention and selecting the appropriate agent. In this review we will explore recent epidemiologic data and clinical trials addressing hypertension and cognition, review pathophysiology of chronic hypertension and effects of brain function, discuss the timing of intervention and finally review opportunities for future research.
(Copyright © 2018. Published by Elsevier Inc.)
Databáze: MEDLINE
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