A 72-Year-Old Patient with Longstanding, Untreated Familial Hypercholesterolemia but no Coronary Artery Calcification: A Case Report.
| Autor: | Johnson KW; Institute for Next Generation Healthcare, Icahn School of Medicine at Mount Sinai, New York, N.Y., USA., Dudley JT; Institute for Next Generation Healthcare, Icahn School of Medicine at Mount Sinai, New York, USA., Bobe JR; Icahn Institute, Genetic and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, USA. |
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| Jazyk: | angličtina |
| Zdroj: | Cureus [Cureus] 2018 Apr 09; Vol. 10 (4), pp. e2452. Date of Electronic Publication: 2018 Apr 09. |
| DOI: | 10.7759/cureus.2452 |
| Abstrakt: | Familial hypercholesterolemia (FH) is a genetic disease associated with persistently elevated levels of low-density lipoprotein cholesterol (LDL-C), which ultimately leads to greatly increased rates of atherosclerosis and cardiovascular disease. Atherosclerosis progression can be clinically approximated through measurement of coronary artery calcification (CAC). CAC can be measured via electron beam computed tomography (EBCT), multi-slice computed tomography (MSCT), or contrast-enhanced CT coronary angiography (CTCA). Here, we present the case of a 72-year-old man with known FH and established hypercholesterolemia who has consistently tested negative for any significant CAC. Competing Interests: The authors have declared that no competing interests exist. |
| Databáze: | MEDLINE |
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