Pancreatic Cancer in Pregnancy Presenting with Thromboembolic Events: Case Report and Review of the Literature.
| Autor: | Wakefield BW; Division of Maternal Fetal Medicine, Department of Obstetrics and Gynecology, University of Colorado School of Medicine, Aurora, Colorado, USA., Masterson CMC; University of Colorado College of Nursing, Aurora, Colorado, USA., Borges MT; Department of Neuroradiology, University of Colorado School of Medicine, Anschutz Medical Campus, Aurora, Colorado, USA., Hurt KJ; Division of Maternal Fetal Medicine, Department of Obstetrics and Gynecology, University of Colorado School of Medicine, Aurora, Colorado, USA. |
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| Jazyk: | angličtina |
| Zdroj: | Gynecologic and obstetric investigation [Gynecol Obstet Invest] 2018; Vol. 83 (4), pp. 404-409. Date of Electronic Publication: 2018 Jun 08. |
| DOI: | 10.1159/000487046 |
| Abstrakt: | Stroke and hepatic vein thrombosis are highly associated with neoplasia but are extremely rare events in young, pregnant women. Rare and recurrent thrombotic events in pregnancy increase the suspicion for occult malignancy. We describe the case of a healthy 31-year-old G2P1 who presented with visual changes and dysarthria during pregnancy. Imaging showed cerebral infarcts. Her thrombophilia evaluation was negative. During delivery, she was diagnosed with fulminant Budd-Chiari Syndrome. Hepatic ultrasound suggested malignancy or metastasis, and postpartum CT scan and biopsy confirmed the diagnosis of Stage IV pancreatic cancer. Although rare in pregnancy, a new diagnosis of malignancy should be considered in patients with recurrent unexplained hypercoagulable complications. We propose an evidence-based algorithm for evaluation of occult malignancy in pregnancy based upon this case and review of the literature. (© 2018 S. Karger AG, Basel.) |
| Databáze: | MEDLINE |
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