Health-related quality of life, temperament, and eating behavior among formula-fed infants in the Philippines: a pilot study.

Autor: Volger S; Rutgers University School of Health Professions, Department of Clinical and Preventive Nutrition Sciences, 65 Bergen Street, Newark, NJ, 07107, USA. volgersh@shp.rutgers.edu.; Nestlé Nutrition Research, King of Prussia, PA, USA. volgersh@shp.rutgers.edu., Estorninos EM; Asian Hospital & Medical Center, Medical Office Building, 2205 Civic Drive, Filinvest Corporate City Alabang, 1708, Muntinlupa City, Philippines., Capeding MR; Asian Hospital & Medical Center, Medical Office Building, 2205 Civic Drive, Filinvest Corporate City Alabang, 1708, Muntinlupa City, Philippines., Lebumfacil J; Wyeth Philippines Inc, 8 Rockwell, Hidalgo Drive, Rockwell Center, Makati City, Philippines., Radler DR; Rutgers University School of Health Professions, Department of Clinical and Preventive Nutrition Sciences, 65 Bergen Street, Newark, NJ, 07107, USA., Scott Parrott J; Rutgers University School of Health Professions, Department of Clinical and Preventive Nutrition Sciences, 65 Bergen Street, Newark, NJ, 07107, USA., Rothpletz-Puglia P; Rutgers University School of Health Professions, Department of Clinical and Preventive Nutrition Sciences, 65 Bergen Street, Newark, NJ, 07107, USA.
Jazyk: angličtina
Zdroj: Health and quality of life outcomes [Health Qual Life Outcomes] 2018 Jun 08; Vol. 16 (1), pp. 121. Date of Electronic Publication: 2018 Jun 08.
DOI: 10.1186/s12955-018-0944-5
Abstrakt: Background: The rising prevalence of childhood obesity in Asia has led to interest in potential risk factors such as infant health-related quality of life (HRQoL), temperament and eating behaviors. This pilot study evaluated the utility of administering parent-reported outcome measures (PROMs) to explore these factors in Filipino infants and examined the relationships between these factors and infant sex, formula intake and weight, over time.
Methods: Forty healthy, 4-week-old, formula-fed infants (n = 20 males) were enrolled in this 6-week, prospective, uncontrolled study during which infants were exclusively fed a standard term infant formula enriched with alpha-lactalbumin. On Day-1 and 42, anthropometrics were measured and mothers completed a 97-item measure of HRQoL [Infant Toddler Quality of Life Questionnaire (ITQOL)] covering 6 infant-focused and 3 parent-focused concepts and a 24-item measure of infant temperament [Infant Characteristics Questionnaire (ICQ)]. At Day-42, mothers also completed an 18-item measure of infant appetite [Baby Eating Behaviour Questionnaire (BEBQ)]. A 3-day formula intake diary was completed before Day-42. Nonparametric statistics were used to evaluate correlations among outcomes and compare outcomes by visit and sex.
Results: Thirty-nine infants completed the study; similar results were observed in males and females. Completion of PROMs was 100% with no missing responses, but Cronbach's α was low for many concept scales scores. ITQOL scores [range 0 (worst)-100 (best)] were generally high (median ≥ 80) except for Day-1 and Day-42 Temperament and Mood and Day-1 General Health Perceptions scores. ITQOL but not ICQ temperament scores improved significantly between Day-1 and Day-42 (P < 0.01). Mean ± standard deviation BEBQ scores (range 1-5) were high for Enjoyment of Food (4.59 ± 0.60) and Food Responsiveness (3.53 ± 0.81), and low for Satiety Responsiveness (2.50 ± 0.73) and Slowness in Eating (1.71 ± 0.60). Better HRQoL scores were significantly (P < 0.05) associated with high General Appetite scores (3 ITQOL concepts, r = 0.32 to 0.54), greater Enjoyment of Food (4 ITQOL concepts, r = 0.35 to 0.42) and low levels of Slowness in Eating (7 ITQOL concepts, r = - 0.32 to - 0.47).
Conclusion: Findings demonstrated the utility of the ITQOL, ICQ and BEBQ for measuring HRQoL, temperament and eating behavior, and the need for further adaptations for use in Filipino infants.
Trial Registration: ClinicalTrials.gov identifier NCT02431377; Registered May 1, 2015.
Databáze: MEDLINE
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