Hearing in Paget's disease of bone.

Autor: Amilibia Cabeza E; Servicio de Otorrinolaringología, Hospital Universitari Germans Trias i Pujol, Badalona (Barcelona), España. Electronic address: emilioamilibia@gmail.com., Holgado Pérez S; Servicio de Reumatología, Hospital Universitari Germans Trias i Pujol, Badalona (Barcelona), España., Pérez Grau M; Servicio de Otorrinolaringología, Hospital Universitari Germans Trias i Pujol, Badalona (Barcelona), España., Moragues Pastor C; Servicio de Reumatología, Hospital Universitari de Bellvitge, L'Hospitalet de Llobregat (Barcelona), España., Roca-Ribas Serdà F; Servicio de Otorrinolaringología, Hospital Universitari Germans Trias i Pujol, Badalona (Barcelona), España., Quer Agustí M; Servicio de Otorrinolaringología, Hospital de la Santa Creu i Sant Pau, Barcelona, España.
Jazyk: English; Spanish; Castilian
Zdroj: Acta otorrinolaringologica espanola [Acta Otorrinolaringol Esp (Engl Ed)] 2019 Mar - Apr; Vol. 70 (2), pp. 89-96. Date of Electronic Publication: 2018 Jun 05.
DOI: 10.1016/j.otorri.2018.04.002
Abstrakt: Introduction and Objectives: Paget's disease of bone (PDB) may lead to hearing loss. The present study was conducted with the aim of measuring, characterizing and determining the risk factors for hearing loss in a group of subjects with PDB.
Methods: An observational, transversal, case-control study was conducted, a cohort of 76 subjects diagnosed with PDB in the case group and a control group of 134 subjects were included. Clinical, demographic and audiometric data were analysed.
Results: The comparative analysis between the subjects in the PDB group and the control group found that the case group showed higher hearing thresholds (39,51dB) compared with the control group (37.28dB) (P=.069) and presented a greater rate of conductive hearing loss (22.76%) than the control group (12.05%) (P=.0062). The study of risk factors for hearing loss found that skull involvement in bone scintigraphy, age and high blood pressure were risk factors for higher impairment in PDB.
Conclusions: The subjects with PDB showed more profound and a higher proportion of conductive hearing loss than the control group. The patients with PDB and skull involvement presented a more severe hearing loss compared with the subjects without skull involvement. Skull involvement and age were found to be risk factors for hearing loss.
(Copyright © 2018 Sociedad Española de Otorrinolaringología y Cirugía de Cabeza y Cuello. Publicado por Elsevier España, S.L.U. All rights reserved.)
Databáze: MEDLINE
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