Re-emergence of human T-lymphotropic viruses in West Africa.
| Autor: | Anyanwu NCJ; Ahmadu Bello University, Faculty of Life Sciences, Department of Microbiology, Zaria, Nigeria; COMSATS University, Department of Biosciences, Islamabad, Pakistan. Electronic address: anyanwunneomaconfidence@gmail.com., Ella EE; Ahmadu Bello University, Faculty of Life Sciences, Department of Microbiology, Zaria, Nigeria., Ohwofasa A; COMSATS University, Department of Biosciences, Islamabad, Pakistan., Aminu M; Ahmadu Bello University, Faculty of Life Sciences, Department of Microbiology, Zaria, Nigeria. |
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| Jazyk: | angličtina |
| Zdroj: | The Brazilian journal of infectious diseases : an official publication of the Brazilian Society of Infectious Diseases [Braz J Infect Dis] 2018 May - Jun; Vol. 22 (3), pp. 224-234. Date of Electronic Publication: 2018 Jun 05. |
| DOI: | 10.1016/j.bjid.2018.05.003 |
| Abstrakt: | Human T-lymphotropic viruses (HTLV) are Deltaretroviruses that infect millions of individuals worldwide via the same transmission routes as HIV. With the aim of exposing the possible re-emergence of HTLV in West Africa since discovery, a systematic review was carried out, focusing on the distribution of the virus types and significance of frequent indeterminate reports, while highlighting the need for mandatory routine blood screening. Capturing relevant data from discovery till date, sources searched were Google Scholar, CrossRef, NCBI (PubMed), MEDLINE, Research Gate, Mendeley, abstracts of Conferences and Proceedings, organization websites and reference lists of selected papers. A total of 2626 references were initially retrieved using search terms: Worldwide prevalence of HTLV, HTLV in Africa, HTLV in West Africa, HTLV subtypes, HTLV 3 and 4 in Africa, HTLV of African origin, HTLV seroindeterminate results, Spread of HTLV. These references were rigorously trimmed down to 76. Although evidence shows that HTLV is still endemic in the region, West Africa lacks recent epidemiological prevalence data. Thorough investigations are needed to ascertain the true cause of indeterminate Western Blot results. It is imperative that routine screening for HTLVs be mandated in West African health care facilities. (Copyright © 2018 Sociedade Brasileira de Infectologia. Published by Elsevier Editora Ltda. All rights reserved.) |
| Databáze: | MEDLINE |
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