Evaluation of the annual killifish Nothobranchius guentheri as a tool for rapid acute toxicity screening.

Autor: Shedd TR; U.S. Army Center for Environmental Health Research, 568 Doughten Drive, Fort Detrick, Maryland 21702-5010., Widder MW; GEO-CENTERS, 568 Doughten Drive, Fort Detrick, Maryland 21702-5010, USA., Toussaint MW; GEO-CENTERS, 568 Doughten Drive, Fort Detrick, Maryland 21702-5010, USA., Sunkel MC; GEO-CENTERS, 568 Doughten Drive, Fort Detrick, Maryland 21702-5010, USA., Hull E; Triops, P.O. Box 10852, Pensacola, Florida 32524, USA.
Jazyk: angličtina
Zdroj: Environmental toxicology and chemistry [Environ Toxicol Chem] 1999 Oct; Vol. 18 (10), pp. 2258-2261.
DOI: 10.1002/etc.5620181020
Abstrakt: This study evaluated the use of Nothobranchius guentheri as a novel organism for rapid acute toxicity screening. A major advantage of the species is that there is no need to maintain a continuous culture to have organisms immediately available for testing. Rather, the embryos are viable under long-term storage conditions and can be hatched within a few hours. The tests require only 24 h with standard laboratory equipment. Sensitivity levels for 11 representative toxicants were comparable to those reported for five of the standard U.S. Environmental Protection Agency test species requiring continuous culture.
(Copyright © 1999 SETAC.)
Databáze: MEDLINE
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