| Autor: |
Wahl RU; Department of Dermatology, Euregional Skin Cancer Center, University Hospital of the RWTH-Aachen, Aachen, Germany., Cacchi C; Department of Pathology, University Hospital of the RWTH-Aachen, Aachen, Germany., Rübben A; Department of Dermatology, Euregional Skin Cancer Center, University Hospital of the RWTH-Aachen, Aachen, Germany. |
| Jazyk: |
angličtina |
| Zdroj: |
Case reports in oncological medicine [Case Rep Oncol Med] 2018 Apr 24; Vol. 2018, pp. 3485326. Date of Electronic Publication: 2018 Apr 24 (Print Publication: 2018). |
| DOI: |
10.1155/2018/3485326 |
| Abstrakt: |
Basal cell carcinoma (BCC) is the most common skin cancer. Metastatic BCC is an extraordinary rare finding observed in only 0.5% of all cases. Until the introduction of the small molecule hedgehog inhibitor vismodegib, patients with metastatic BCC were treated with chemotherapy, most frequently platinum-based with mixed responses to therapy. We present the case of a 55-year-old Caucasian man who suffered from BCC on his left arm with lymph node and pulmonary metastases. Sonic hedgehog blockade with vismodegib only induced a short remission, and the patient succumbed to the cancer. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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