| Autor: |
Filatova MP, Krit NA, Beschastnaia NV, Blokhina AV, Kozlova NI |
| Jazyk: |
ruština |
| Zdroj: |
Bioorganicheskaia khimiia [Bioorg Khim] 1985 Jan; Vol. 11 (1), pp. 21-30. |
| Abstrakt: |
The synthesis of 5 analogues of the effective inhibitor of peptidyl dipeptidase, teprotide, has been carried out. The inhibitory and bradykinin-potentiating activity of these compounds has been assayed. N-Terminal pyroglutamic acid and positive charge of arginine in position 4 were found to be essential for biological activity of the inhibitor. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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