Energy drink exposures reported to Texas poison centers: Analysis of adverse incidents in relation to total sales, 2010-2014.

Autor: Borron SW; Texas Tech University Health Sciences Center El Paso, Department of Emergency Medicine, 4801 Alberta Ave., Suite B3200, El Paso, TX 79905, United States; West Texas Regional Poison Center at University Medical Center of El Paso, 4815 Alameda Ave., El Paso, TX 79905, United States; SafetyCall International, PLLC, 3600 American Blvd. W., Suite 725, Bloomington, MN 55431, United States. Electronic address: stephen.borron@ttuhsc.edu., Watts SH; Texas Tech University Health Sciences Center El Paso, Department of Emergency Medicine, 4801 Alberta Ave., Suite B3200, El Paso, TX 79905, United States., Herrera J; Texas Tech University Health Sciences Center El Paso, Department of Emergency Medicine, 4801 Alberta Ave., Suite B3200, El Paso, TX 79905, United States., Larson J; Texas Tech University Health Sciences Center El Paso, Department of Emergency Medicine, 4801 Alberta Ave., Suite B3200, El Paso, TX 79905, United States., Baeza S; West Texas Regional Poison Center at University Medical Center of El Paso, 4815 Alameda Ave., El Paso, TX 79905, United States., Kingston RL; University of Minnesota College of Pharmacy, 308 SE. Harvard St., Minneapolis, MN 55455, United States; SafetyCall International, PLLC, 3600 American Blvd. W., Suite 725, Bloomington, MN 55431, United States.
Jazyk: angličtina
Zdroj: Regulatory toxicology and pharmacology : RTP [Regul Toxicol Pharmacol] 2018 Aug; Vol. 97, pp. 1-14. Date of Electronic Publication: 2018 May 21.
DOI: 10.1016/j.yrtph.2018.05.008
Abstrakt: The ill-defined term "energy drink" includes a disparate group of products (beverages, shots, concentrates, and workout powders) having large differences in caffeine content and concentration and intended use. Hence, inaccurate conclusions may be drawn when describing adverse events associated with "energy drinks". The FDA is considering new regulation of these products but product specificity is needed to evaluate safety. To help address this, we queried Texas Poison Center Network data for single substance exposures to "energy drinks" from 2010 to 2014, then analyzed adverse events by product type. We specifically compared energy beverage exposures with sales data for the same time period to evaluate the safety profile of this category of energy drinks. Among 855 documented "energy drink" exposures, poison center-determined outcome severity revealed 291 with no/minimal effects, 417 judged nontoxic or minor/not followed, 64 moderate and 4 major effects, and no deaths. Serious complications included 2 seizures and 1 episode of ventricular tachycardia. Outcome severity by category for beverages: 11 moderate/1 major effects (none in children <17 years); shots: 19 moderate/2 major; non-liquids: 16 moderate/1 major; concentrates: 7 moderate; unknown: 10 moderate. Call incidence to poison centers for beverage type exposures was 0.58 (for moderate effects) and 0.053 (for major) per hundred million units sold. Small volume and concentrated products were associated with a greater number of adverse effects than beverage versions of "energy drinks".
(Copyright © 2018 Elsevier Inc. All rights reserved.)
Databáze: MEDLINE
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