Nuts as a replacement for carbohydrates in the diabetic diet: a reanalysis of a randomised controlled trial.
Autor: | Jenkins DJA; Department of Nutritional Sciences, Faculty of Medicine, University of Toronto, 5th Floor, Medical Science Building (MSB), 1 Kings College Circle, Toronto, ON, M5S 1A8, Canada. david.jenkins@utoronto.ca.; Department of Medicine, Faculty of Medicine, University of Toronto, Toronto, ON, Canada. david.jenkins@utoronto.ca.; Clinical Nutrition and Risk Factor Modification Centre, St Michael's Hospital, Toronto, ON, Canada. david.jenkins@utoronto.ca.; Division of Endocrinology and Metabolism, St Michael's Hospital, Toronto, ON, Canada. david.jenkins@utoronto.ca.; Li Ka Shing Knowledge Institute, St Michael's Hospital, Toronto, ON, Canada. david.jenkins@utoronto.ca., Kendall CWC; Department of Nutritional Sciences, Faculty of Medicine, University of Toronto, 5th Floor, Medical Science Building (MSB), 1 Kings College Circle, Toronto, ON, M5S 1A8, Canada.; Clinical Nutrition and Risk Factor Modification Centre, St Michael's Hospital, Toronto, ON, Canada.; College of Pharmacy and Nutrition, University of Saskatchewan, Saskatoon, SK, Canada., Lamarche B; School of Nutrition, Institute of Nutrition and Functional Foods, Laval University, Quebec City, QC, Canada., Banach MS; Clinical Nutrition and Risk Factor Modification Centre, St Michael's Hospital, Toronto, ON, Canada., Srichaikul K; Department of Nutritional Sciences, Faculty of Medicine, University of Toronto, 5th Floor, Medical Science Building (MSB), 1 Kings College Circle, Toronto, ON, M5S 1A8, Canada.; Clinical Nutrition and Risk Factor Modification Centre, St Michael's Hospital, Toronto, ON, Canada.; Division of Family and Community Medicine, St Michael's Hospital, Toronto, ON, Canada., Vidgen E; Department of Nutritional Sciences, Faculty of Medicine, University of Toronto, 5th Floor, Medical Science Building (MSB), 1 Kings College Circle, Toronto, ON, M5S 1A8, Canada.; Clinical Nutrition and Risk Factor Modification Centre, St Michael's Hospital, Toronto, ON, Canada., Mitchell S; Clinical Nutrition and Risk Factor Modification Centre, St Michael's Hospital, Toronto, ON, Canada., Parker T; Clinical Nutrition and Risk Factor Modification Centre, St Michael's Hospital, Toronto, ON, Canada., Nishi S; Department of Nutritional Sciences, Faculty of Medicine, University of Toronto, 5th Floor, Medical Science Building (MSB), 1 Kings College Circle, Toronto, ON, M5S 1A8, Canada.; Clinical Nutrition and Risk Factor Modification Centre, St Michael's Hospital, Toronto, ON, Canada., Bashyam B; Department of Nutritional Sciences, Faculty of Medicine, University of Toronto, 5th Floor, Medical Science Building (MSB), 1 Kings College Circle, Toronto, ON, M5S 1A8, Canada.; Clinical Nutrition and Risk Factor Modification Centre, St Michael's Hospital, Toronto, ON, Canada., de Souza RJ; Department of Nutritional Sciences, Faculty of Medicine, University of Toronto, 5th Floor, Medical Science Building (MSB), 1 Kings College Circle, Toronto, ON, M5S 1A8, Canada.; Clinical Nutrition and Risk Factor Modification Centre, St Michael's Hospital, Toronto, ON, Canada.; Department of Health Research Methods, Evidence, and Impact, McMaster University, Hamilton, ON, Canada., Ireland C; Clinical Nutrition and Risk Factor Modification Centre, St Michael's Hospital, Toronto, ON, Canada., Pichika SC; Department of Nutritional Sciences, Faculty of Medicine, University of Toronto, 5th Floor, Medical Science Building (MSB), 1 Kings College Circle, Toronto, ON, M5S 1A8, Canada.; Clinical Nutrition and Risk Factor Modification Centre, St Michael's Hospital, Toronto, ON, Canada.; Department of Mathematics and Statistics, University of Windsor, Windsor, ON, Canada., Beyene J; Department of Health Research Methods, Evidence, and Impact, McMaster University, Hamilton, ON, Canada., Sievenpiper JL; Department of Nutritional Sciences, Faculty of Medicine, University of Toronto, 5th Floor, Medical Science Building (MSB), 1 Kings College Circle, Toronto, ON, M5S 1A8, Canada.; Clinical Nutrition and Risk Factor Modification Centre, St Michael's Hospital, Toronto, ON, Canada.; Division of Endocrinology and Metabolism, St Michael's Hospital, Toronto, ON, Canada.; Li Ka Shing Knowledge Institute, St Michael's Hospital, Toronto, ON, Canada., Josse RG; Department of Nutritional Sciences, Faculty of Medicine, University of Toronto, 5th Floor, Medical Science Building (MSB), 1 Kings College Circle, Toronto, ON, M5S 1A8, Canada.; Department of Medicine, Faculty of Medicine, University of Toronto, Toronto, ON, Canada.; Clinical Nutrition and Risk Factor Modification Centre, St Michael's Hospital, Toronto, ON, Canada.; Division of Endocrinology and Metabolism, St Michael's Hospital, Toronto, ON, Canada.; Li Ka Shing Knowledge Institute, St Michael's Hospital, Toronto, ON, Canada. |
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Jazyk: | angličtina |
Zdroj: | Diabetologia [Diabetologia] 2018 Aug; Vol. 61 (8), pp. 1734-1747. Date of Electronic Publication: 2018 May 23. |
DOI: | 10.1007/s00125-018-4628-9 |
Abstrakt: | Aims/hypothesis: In line with current advice, we assessed the effect of replacing carbohydrate consumption with mixed nut consumption, as a source of unsaturated fat, on cardiovascular risk factors and HbA Methods: A total of 117 men and postmenopausal women with type 2 diabetes who were taking oral glucose-lowering agents and with HbA Results: A total of 108 participants had post-intervention data available for analysis (full-dose nut group, n = 40; full-dose muffin group, n = 35; half-dose nut group, n = 33). Compared with the full-dose muffin diet, the full-dose nut diet provided 9.2% (95% CI 7.1, 11.3) greater total energy intake from monounsaturated fat. The full-dose nut diet (median intake, 75 g/day) also reduced HbA Conclusions/interpretation: Nut intake as a replacement for carbohydrate consumption improves glycaemic control and lipid risk factors in individuals with type 2 diabetes. Trial Registration: ClinicalTrials.gov NCT00410722 FUNDING: The study was funded by the International Tree Nut Council Nutrition Research and Education Foundation, the Peanut Institute, Loblaw Companies and the Canada Research Chairs Program of the Government of Canada. |
Databáze: | MEDLINE |
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