Diffuse idiopathic pulmonary neuroendocrine cell hyperplasia: Report of two cases.

Autor:	García-Fontán E; Thoracic Surgery Department, Alvaro Cunqueiro University Clinical Hospital, EOXI, Vigo, Spain., Blanco Ramos M; Thoracic Surgery Department, Alvaro Cunqueiro University Clinical Hospital, EOXI, Vigo, Spain. Electronic address: montseblancoramos@hotmail.com., García JS; Thoracic Surgery Department, Alvaro Cunqueiro University Clinical Hospital, EOXI, Vigo, Spain., Carrasco R; Thoracic Surgery Department, Alvaro Cunqueiro University Clinical Hospital, EOXI, Vigo, Spain., Cañizares MÁ; Thoracic Surgery Department, Alvaro Cunqueiro University Clinical Hospital, EOXI, Vigo, Spain., González Piñeiro A; Pathology Department, Alvaro Cunqueiro University Clinical Hospital, EOXI, Vigo, Spain.
Jazyk:	English; Spanish; Castilian
Zdroj:	Medicina clinica [Med Clin (Barc)] 2019 Feb 01; Vol. 152 (3), pp. 104-106. Date of Electronic Publication: 2018 May 20.
DOI:	10.1016/j.medcli.2018.03.036
Abstrakt:	Introduction: Diffuse idiopathic pulmonary neuroendocrine cell hyperplasia (DIPNECH) is a rare disorder characterized by a proliferation of neuroendocrine cells within the lung. It is classically described as a disease with persistent cough, dyspnea and wheezing in non-smoker middle aged females. CT of the chest reveals diffuse air trapping with mosaic pattern. Patients and Methods: We present two cases of DIPNECH that were sent to our department to perform a lung biopsy with the diagnostic suspicion of diffuse interstitial disease. Both cases were women with a history of chronic cough and moderate effort dyspnea. Results and Discussion: The aim of this paper is that physicians take into account this diagnostic entity before treating as an asthmatic a patient with these characteristics, not forgetting that they are prenoplastic lesions. (Copyright © 2018 Elsevier España, S.L.U. All rights reserved.)
Databáze:	MEDLINE
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