The clinical value of the patient-reported multiple sclerosis neuropsychological screening questionnaire.

Autor: Nauta IM; Department of Neurology, Amsterdam Neuroscience, MS Center Amsterdam, VU University Medical Center, Amsterdam, The Netherlands., Balk LJ; Department of Neurology, Amsterdam Neuroscience, MS Center Amsterdam, VU University Medical Center, Amsterdam, The Netherlands., Sonder JM; Department of Neurology, Amsterdam Neuroscience, MS Center Amsterdam, VU University Medical Center, Amsterdam, The Netherlands., Hulst HE; Department of Anatomy and Neurosciences, Amsterdam Neuroscience, MS Center Amsterdam, VU University Medical Center, Amsterdam, The Netherlands., Uitdehaag BM; Department of Neurology, Amsterdam Neuroscience, MS Center Amsterdam, VU University Medical Center, Amsterdam, The Netherlands., Fasotti L; Donders Institute for Brain, Cognition and Behaviour, Radboud University, Nijmegen, The Netherlands; Klimmendaal Rehabilitation Center, Arnhem, The Netherlands., de Jong BA; Department of Neurology, Amsterdam Neuroscience, MS Center Amsterdam, VU University Medical Center, Amsterdam, The Netherlands.
Jazyk: angličtina
Zdroj: Multiple sclerosis (Houndmills, Basingstoke, England) [Mult Scler] 2019 Oct; Vol. 25 (11), pp. 1543-1546. Date of Electronic Publication: 2018 May 18.
DOI: 10.1177/1352458518777295
Abstrakt: Background: Cognitive problems are difficult to identify in patients with multiple sclerosis (MS).
Objective: To investigate the clinical applicability of the patient-reported MS Neuropsychological Screening Questionnaire (MSNQ-P).
Methods: Cut-off scores were determined to differentiate between cognitively impaired ( n  = 90), mildly cognitively impaired ( n  = 115), and cognitively preserved ( n  = 147) MS patients using receiver operating characteristic analyses.
Results: We could not define specific and sensitive cut-off scores. Higher scores (≥27) did indicate cognitive impairment. Among patients with a higher education, lower scores (<12) indicated intact cognition.
Conclusion: Certain scores can indicate intact or impaired cognitive function. Still, MSNQ-P scores should be interpreted with caution.
Databáze: MEDLINE
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