An Update on the Global Epidemic of Human T-Cell Lymphotrophic Virus Type-I (HTLV-I).

Autor: Edlich R; Legacy Verified Level I Shock Trauma Center Pediatrics and Adults, Legacy Emanual Hospital; and Plastic Surgery, Biomedical Engineering and Emergency Medicine, University of Virginia Health System, USA., Hill LG; Plastic Surgery Research Program, University of Virginia Health System, Charlottesville, Virginia., Williams FM; Harvard Medical School, Boston, Massachusetts.
Jazyk: angličtina
Zdroj: Journal of long-term effects of medical implants [J Long Term Eff Med Implants] 2017; Vol. 27 (2-4), pp. 355-368.
DOI: 10.1615/JLongTermEffMedImplants.v27.i2-4.160
Abstrakt: Infection with human T-cell lymphotrophic virus-I (HTLV-I) is now a global epidemic, affecting 10 to 20 million people. This virus has been linked to life-threatening, incurable diseases, adult T-cell leukemia/lymphoma (ATLL), and HTLV-I associated myelopathy/tropical spastic paraparesis (HAM/TSP), as well as several chronic illnesses, such as uveitis and dermatitis. The cumulative lifetime risk of developing these incurable diseases is approximately 5% in asymptomatic patients. For operating room personnel performing surgery among patients from high-risk groups, HTLV-I and its associated diseases are presenting an increasing challenge. This report describes its transmission, seroprevalence, treatment, and public health initiatives that must be instituted to prevent the spread of this retrovirus. Coinfection with HTLV-I and human immunodeficiency virus (HIV) has been shown to accelerate the progression of acquired immune deficiency syndrome (AIDS).
Databáze: MEDLINE