A Concise Review of the Epidemiology and Diagnostics of Rickettsioses: Rickettsia and Orientia spp.
| Autor: | Abdad MY; National Centre for Infectious Diseases, Singapore yazid_abdad@ttsh.com.sg.; Department of Infectious Diseases, Institute of Infectious Diseases and Epidemiology, Tan Tock Seng Hospital, Singapore., Abou Abdallah R; Centre National de Référence des Rickettsia, Coxiella et Bartonella, Faculté de Médecine, Université de la Méditerranée, Aix-en-Provence, France., Fournier PE; Centre National de Référence des Rickettsia, Coxiella et Bartonella, Faculté de Médecine, Université de la Méditerranée, Aix-en-Provence, France., Stenos J; Australian Rickettsial Reference Laboratory, University Hospital, Geelong, Victoria, Australia., Vasoo S; National Centre for Infectious Diseases, Singapore.; Department of Infectious Diseases, Institute of Infectious Diseases and Epidemiology, Tan Tock Seng Hospital, Singapore.; Lee Kong Chian School of Medicine, Nanyang Technological University, Singapore. |
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| Jazyk: | angličtina |
| Zdroj: | Journal of clinical microbiology [J Clin Microbiol] 2018 Jul 26; Vol. 56 (8). Date of Electronic Publication: 2018 Jul 26 (Print Publication: 2018). |
| DOI: | 10.1128/JCM.01728-17 |
| Abstrakt: | Rickettsioses are globally distributed and caused by the family Rickettsiaceae , which comprise a diverse and expanding list of organisms. These include two genera, Rickettsia and Orientia Serology has been traditionally the mainstay of diagnosis, although this has been limited by cross-reactions among closely related members and diminished sensitivity/utility in the acute phase of illness. Other techniques, such as nucleic acid amplification tests using blood specimens or tissue swabs/biopsy specimens, sequencing, and mass spectrometry, have emerged in recent years for both pathogen and vector identification. This paper provides a concise review of the rickettsioses and the traditional and newer technologies available for their diagnosis. (Copyright © 2018 American Society for Microbiology.) |
| Databáze: | MEDLINE |
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