Identifying chronic heavy alcohol use in emergency general surgery patients: a pilot study.

Autor:	Matar MM; Department of Surgery, Medical University of South Carolina, Charleston, South Carolina, USA., Jewett B; Department of Surgery, Trident Medical Center, Charleston, South Carolina, USA., Fakhry SM; Department of Surgery, Medical University of South Carolina, Charleston, South Carolina, USA., Wilson DA; Department of Surgery, Medical University of South Carolina, Charleston, South Carolina, USA., Ferguson PL; Department of Surgery, Medical University of South Carolina, Charleston, South Carolina, USA., Anton RF; Department of Surgery, Medical University of South Carolina, Charleston, South Carolina, USA.; The Charleston Alcohol Center, Medical University of South Carolina, Charleston, South Carolina, USA., Sakran JV; Department of Surgery, Medical University of South Carolina, Charleston, South Carolina, USA.; Division of Acute Care Surgery, The Johns Hopkins University, The Johns Hopkins Hospital, Baltimore, Maryland, USA.
Jazyk:	angličtina
Zdroj:	Trauma surgery & acute care open [Trauma Surg Acute Care Open] 2017 Sep 29; Vol. 2 (1), pp. e000098. Date of Electronic Publication: 2017 Sep 29 (Print Publication: 2017).
DOI:	10.1136/tsaco-2017-000098
Abstrakt:	Background: Chronic heavy alcohol (CHA) use has been associated with perioperative complications. Emergency general surgery (EGS) patients are not routinely screened for CHA. If screened, it is usually for hazardous use of alcohol, using a survey such as the Alcohol Use Disorders Identification Test (AUDIT). This study screened EGS patients for CHA use using serum carbohydrate-deficient transferrin (%dCDT) level, a biomarker that has been validated as an indicator for CHA use, as well as the AUDIT. The purpose of this study was to determine the percent of EGS patients with CHA (as indicated by elevated %dCDT), and the relationship between %dCDT and AUDIT. Secondary aims included comparing the characteristics of EGS patients with and without CHA use, and evaluating the association of CHA use with negative clinical outcomes. Methods: EGS patients aged 21 and older admitted to the general surgery inpatient service of a tertiary hospital from July 2014 to June 2016 were invited to participate in this study. %dCDT levels above 1.7% were considered positive for CHA use, as were AUDIT scores ≥8. Results: 195 EGS patients were screened for inclusion and 91 (46.7%) agreed to participate. 14 (15.4%) were positive for hazardous alcohol use on AUDIT and 5 (5.5%) were positive for CHA by %dCDT. Positive predictive value of AUDIT for CHA was 21.4%. There was no correlation between positive scores on AUDIT and %dCDT. Discussion: Identifying at risk patients early on in their hospital course may allow clinicians to institute treatments to mitigate and/or circumvent complications in such patients. This pilot study determined that 17.6% of participating EGS patients were positive for some type of alcohol misuse, but only 5.5% had CHA. Further research is needed to determine whether routine use of %dCDT would be beneficial in reducing perioperative complications in this patient population. Level of Evidence: III (diagnostic test). Competing Interests: Competing interests: None declared.
Databáze:	MEDLINE
Externí odkaz:	Zobrazit plný text záznamu