[Research on the rest functional magnetic resonance imaging before and after smoking cessation].

Autor: Mo S; Affiliated Hospital of Guilin Medical University, Guilin, Guangxi 541001, P.R.China., Feng S; Affiliated Hospital of Guilin Medical University, Guilin, Guangxi 541001, P.R.China., Chen H; School of Life and Environmental Sciences, Guilin University of Electronic Technology, Guilin, Guangxi 541004, P.R.China.hongbochen@163.com.
Jazyk: čínština
Zdroj: Sheng wu yi xue gong cheng xue za zhi = Journal of biomedical engineering = Shengwu yixue gongchengxue zazhi [Sheng Wu Yi Xue Gong Cheng Xue Za Zhi] 2018 Feb 25; Vol. 35 (1), pp. 87-91.
DOI: 10.7507/1001-5515.201609026
Abstrakt: The aim of this paper is to reveal the change of the brain function for nicotine addicts after smoking cessation, and explore the basis of neural physiology for the nicotine addicts in the process of smoking cessation. Fourteen subjects, who have a strong dependence on nicotine, have agreed to give up smoking and insist on completing the test, and 11 volunteers were recruited as the controls. The resting state functional magnetic resonance imaging and the regional homogeneity (ReHo) algorithm have been used to study the neural activity before and after smoking cessation. A two factors mixed design was used to investigate within-group effects and between-group effects. After 2 weeks' smoking cessation, the increased ReHo value were exhibited in the brain area of supplementary motor area, paracentral lobule, calcarine, cuneus and lingual gyrus. It suggested that the synchronization of neural activity was enhanced in these brain areas. And between-group interaction effects were appeared in supplementary motor area, paracentral lobule, precentral gyrus, postcentral gyrus, and superior frontal gyrus. The results indicate that the brain function in supplementary motor area of smoking addicts would be enhanced significantly after 2 weeks' smoking cessation.
Databáze: MEDLINE