Foetomaternal outcomes of hepatitis E infection outbreak in North India.

Autor: Gautam N; Department of Microbiology, Virology Research Diagnostic Laboratory, Indira Gandhi Medical College, Shimla, Himachal Pradesh, India., Ganju S; Department of Obstetrics and Gynaecology, Kamla Nehru State Hospital for Mother and Child, Indira Gandhi Medical College, Shimla, Himachal Pradesh, India., Ganju SA; Department of Microbiology, Indira Gandhi Medical College, Shimla, Himachal Pradesh, India., Walia S; Department of Microbiology, Virology Research Diagnostic Laboratory, Indira Gandhi Medical College, Shimla, Himachal Pradesh, India., Kumar AK; Department of Microbiology, Indira Gandhi Medical College, Shimla, Himachal Pradesh, India.
Jazyk: angličtina
Zdroj: Indian journal of medical microbiology [Indian J Med Microbiol] 2018 Jan-Mar; Vol. 36 (1), pp. 121-123.
DOI: 10.4103/ijmm.IJMM_16_422
Abstrakt: Hepatitis E infection (HEV) in pregnant females, especially in the third trimester is associated with poor foetomaternal outcomes. However, the mechanisms of severe liver injury remain obscure. In a recent HEV outbreak in North India, six pregnant females were detected to be positive for HEV infection with concomitant hepatitis A infection in three pregnant females. None of the pregnant females were positive for hepatitis B or hepatitis C infection. The mortality was 50% in pregnant females. In an outbreak, besides, testing for hepatitis markers and understanding the pathogenesis of HEV infection in pregnancy, improving basic hygienic standards is of utmost importance.
Competing Interests: There are no conflicts of interest
Databáze: MEDLINE
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