A compact instrument to measure perfusion of vasculature in transplanted maxillofacial free flaps.

Autor: Kolodziejski NJ; Radiation Monitoring Devices, Inc., 44 Hunt St., Watertown, MA, 02472 USA., Stapels CJ; Radiation Monitoring Devices, Inc., 44 Hunt St., Watertown, MA, 02472 USA., McAdams DR; Radiation Monitoring Devices, Inc., 44 Hunt St., Watertown, MA, 02472 USA., Fernandez DE; Radiation Monitoring Devices, Inc., 44 Hunt St., Watertown, MA, 02472 USA., Podolsky MJ; Radiation Monitoring Devices, Inc., 44 Hunt St., Watertown, MA, 02472 USA., Farkas D; Radiation Monitoring Devices, Inc., 44 Hunt St., Watertown, MA, 02472 USA.; Northeastern Univ., Boston, MA USA., Ward BB; Department of Oral and Maxillofacial Surgery, Univ. of Michigan, Ann Arbor, MI 48109, USA., Vartarian M; Department of Oral and Maxillofacial Surgery, Univ. of Michigan, Ann Arbor, MI 48109, USA., Feinberg SE; Department of Oral and Maxillofacial Surgery, Univ. of Michigan, Ann Arbor, MI 48109, USA., Lee SY; Department of Biomedical Engineering, Univ. of Michigan, Ann Arbor, MI 48109, USA., Parikh U; Department of Biomedical Engineering, Univ. of Michigan, Ann Arbor, MI 48109, USA., Mycek MA; Department of Biomedical Engineering, Univ. of Michigan, Ann Arbor, MI 48109, USA., Christian JF; Radiation Monitoring Devices, Inc., 44 Hunt St., Watertown, MA, 02472 USA.
Jazyk: angličtina
Zdroj: Proceedings of SPIE--the International Society for Optical Engineering [Proc SPIE Int Soc Opt Eng] 2016 Feb; Vol. 9715. Date of Electronic Publication: 2016 Mar 04.
DOI: 10.1117/12.2212872
Abstrakt: The vascularization and resulting perfusion of transferred tissues are critical to the success of grafts in buried free flap transplantations. To enable long-term clinical monitoring of grafted tissue perfusion during neovascularization and endothelialization, we are developing an implantable instrument for the continuous monitoring of perfusion using diffuse correlation spectroscopy (DCS), and augmented with diffuse reflectance spectroscopy (DRS). This work discusses instrument construction, integration, and preliminary results using a porcine graft model.
Databáze: MEDLINE